Relationships of self-perceived age with geriatric assessment domains in older adults with cancer

Kah Poh Loh, Paul Duberstein, Jason Zittel, Lianlian Lei, Eva Culakova, Huiwen Xu, Sandy Plumb, Marie A. Flannery, Allison Magnuson, Javier Bautista, Marsha Wittink, Nikesha Gilmore, Valerie Targia, Alison Conlin, Jeffrey Berenberg, Victor G. Vogel, Supriya G. Mohile

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Objectives: Older self-perceived age is associated with poor health and higher healthcare utilization in the geriatric population. We evaluated the associations of self-perceived age with geriatric assessment (GA) domain impairments in older adults with cancer. Methods: This was a secondary analysis of baseline data from a GA cluster-randomized trial (URCC 13070; PI: Mohile). We included patients aged ≥70 with incurable stage III/IV solid tumor or lymphoma considering or receiving treatment and had ≥1 GA domain impairment other than polypharmacy. Multivariate analyses were used to evaluate the associations of age difference between chronological and self-perceived age (categorized into “feeling younger than chronological age” vs. “feeling the same or older than their chronological age”) with GA domain impairments. Results: We included 533 patients; mean age was 76.6 (SD 5.2). On multivariate analyses, compared to those who felt younger than their chronological age, those who felt the same or older were more likely to have impairments in physical performance [Adjusted Odds Ratio (AOR) 5.42, 95% Confidence Interval (CI) 1.69–17.40)], functional status (AOR 2.31, 95% CI 1.73–3.07), comorbidity (AOR 1.62, 95% CI 1.20–2.19), psychological health (AOR 2.62, 95% CI 1.85–3.73), and nutrition (AOR 1.65, 95% CI 1.20–2.28). They were also more likely to screen positively for polypharmacy (AOR 1.86, 95% CI 1.30–2.65). Conclusions: Older adults with cancer who felt the same or older than their chronological age were more likely to have GA domain impairments. Further studies are needed to better understand the relationships between self-perceived age, aging-related conditions, and outcomes in this population.

Original languageEnglish (US)
Pages (from-to)1006-1010
Number of pages5
JournalJournal of Geriatric Oncology
Volume11
Issue number6
DOIs
StatePublished - Jul 2020
Externally publishedYes

Keywords

  • Functional status
  • Geriatric assessment
  • Physical performance
  • Psychological health
  • Self-perceived age

ASJC Scopus subject areas

  • Oncology
  • Geriatrics and Gerontology

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