Release of cholecystokinin in response to food and intraduodenal fat in pigs, dogs and man

P. Lilja, I. Wiener, K. Inoue, G. M. Fried, G. H. Greeley, J. C. Thompson

    Research output: Contribution to journalArticle

    49 Scopus citations

    Abstract

    The present study was done to compare endogenous cholecystokinin-33 release in response to physiologic stimuli (meal, fat) in pigs, dogs and man. Plasma levels of cholecystokinin-33 were monitored using a radioimmunoassay for cholecystokinin which detects only cholecystokinin-33 and cholecystokinin-39. Ingestion of a meal caused release of cholecystokinin-33 within five, 20 and 120 minutes in man, pigs and dogs, respectively. Intraduodenal administration of corn oil resulted in a significant release of cholecystokinin-33 within 20 minutes in dogs, pigs and man.

    Original languageEnglish (US)
    Pages (from-to)557-561
    Number of pages5
    JournalSurgery Gynecology and Obstetrics
    Volume159
    Issue number6
    StatePublished - Dec 1 1984

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    ASJC Scopus subject areas

    • Surgery
    • Obstetrics and Gynecology

    Cite this

    Lilja, P., Wiener, I., Inoue, K., Fried, G. M., Greeley, G. H., & Thompson, J. C. (1984). Release of cholecystokinin in response to food and intraduodenal fat in pigs, dogs and man. Surgery Gynecology and Obstetrics, 159(6), 557-561.