Renal allograft abscesses following transplant: Case report and literature review

Mohammadali Mohajel Shoja, Mohamad R. Ardalan, Jalal Etemadi, R. Shane Tubbs, Mojtaba Varshochi

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Intrarenal and perinephric abscess formations are infrequent infectious complications in kidney allograft recipients. A 37-year-old man who was a victim of mustard gas chemical weapons from the Iran-Iraq war received a live-donor kidney transplant for end-stage renal disease. The posttransplant course was complicated by clinical rejection, which subsided after a 2-week infusion of antithymocyte globulin. One month subsequent to this, the patient presented with renal allograft dysfunction and multiple intrarenal abscesses. Culture from the purulent aspirate of a percutaneously drained renal abscess revealed multidrug-resistant Pseudomonas aeruginosa. A concomitant acute cytomegalovirus infection was detected based on positive serologic tests. Treatment with intravenous meropenem (3 g/day for 3 weeks) and oral ciprofloxacin was begun, which resulted in the complete resolution of the intrarenal abscesses. To our knowledge, this report represents the first description of pseudomonal renal abscesses in a renal transplant recipient. A review of the relevant literature is presented.

Original languageEnglish (US)
Pages (from-to)720-723
Number of pages4
JournalExperimental and Clinical Transplantation
Volume5
Issue number2
StatePublished - Dec 1 2007
Externally publishedYes

    Fingerprint

Keywords

  • Cytomegalovirus
  • Kidney
  • Mustard gas
  • Pseudomonas aeruginosa
  • Transplantation

ASJC Scopus subject areas

  • Transplantation

Cite this

Mohajel Shoja, M., Ardalan, M. R., Etemadi, J., Tubbs, R. S., & Varshochi, M. (2007). Renal allograft abscesses following transplant: Case report and literature review. Experimental and Clinical Transplantation, 5(2), 720-723.