Renal artery stenosis in kidney transplants

Assessment of the risk factors

Jalal Etemadi, Khosro Rahbar, Ali Nobakht Haghighi, Nazila Bagheri, Kianoosh Falaknazi, Mohammad Reza Ardalan, Kamyar Ghabili, Mohammadali Mohajel Shoja

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background: Transplant renal artery stenosis (TRAS) is an important cause of hypertension and renal allograft dysfunction occurring in kidney transplant recipients. However, conflicting predisposing risk factors for TRAS have been reported in the literature. Objective: The aim of the present study was to assess the potential correlation between possible risk factors and TRAS in a group of living donor renal transplant recipients 1 year after the renal transplantation. Methods: We evaluated the presence of renal artery stenosis in 16 recipients who presented with refractory hypertension and/or allograft dysfunction 1 year after renal transplantation. Screening for TRAS was made by magnetic resonance angiography and diagnosis was confirmed by conventional renal angiography. Age, gender, history of acute rejection, plasma lipid profile, serum creatinine, blood urea nitrogen, serum uric acid, calcium phosphate (CaPO4) product, alkaline phosphatase, fasting blood sugar, hemoglobin, and albumin were compared between the TRAS and non-TRAS groups. Results: Of 16 kidney transplant recipients, TRAS was diagnosed in three patients (two men and one woman). High levels of calcium, phosphorous, CaPO4 product, and low-density lipoprotein (LDL) cholesterol were significantly correlated with the risk of TRAS 1 year after renal transplantation (P < 0.05). Serum level of uric acid tended to have a significant correlation (P = 0.051). Conclusion: Correlation between high CaPO4 product, LDL cholesterol, and perhaps uric acid and TRAS in living donor renal transplant recipients 1 year after renal transplantation might suggest the importance of early detection and tight control of these potential risk factors.

Original languageEnglish (US)
Pages (from-to)503-507
Number of pages5
JournalVascular Health and Risk Management
Volume7
Issue number1
DOIs
StatePublished - Jan 1 2011
Externally publishedYes

Fingerprint

Renal Artery Obstruction
Transplants
Kidney
Kidney Transplantation
Uric Acid
Living Donors
LDL Cholesterol
Allografts
Serum
Renal Hypertension
Magnetic Resonance Angiography
Blood Urea Nitrogen
Causality
Alkaline Phosphatase
Blood Glucose
Albumins
Fasting
Creatinine
Angiography
Hemoglobins

Keywords

  • Atherosclerosis
  • Calcium phosphate product
  • Low density lipoprotein
  • Transplant renal artery stenosis
  • Uric acid

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pharmacology (medical)
  • Public Health, Environmental and Occupational Health
  • Hematology
  • Endocrinology, Diabetes and Metabolism

Cite this

Etemadi, J., Rahbar, K., Haghighi, A. N., Bagheri, N., Falaknazi, K., Ardalan, M. R., ... Mohajel Shoja, M. (2011). Renal artery stenosis in kidney transplants: Assessment of the risk factors. Vascular Health and Risk Management, 7(1), 503-507. https://doi.org/10.2147/VHRM.S19645

Renal artery stenosis in kidney transplants : Assessment of the risk factors. / Etemadi, Jalal; Rahbar, Khosro; Haghighi, Ali Nobakht; Bagheri, Nazila; Falaknazi, Kianoosh; Ardalan, Mohammad Reza; Ghabili, Kamyar; Mohajel Shoja, Mohammadali.

In: Vascular Health and Risk Management, Vol. 7, No. 1, 01.01.2011, p. 503-507.

Research output: Contribution to journalArticle

Etemadi, J, Rahbar, K, Haghighi, AN, Bagheri, N, Falaknazi, K, Ardalan, MR, Ghabili, K & Mohajel Shoja, M 2011, 'Renal artery stenosis in kidney transplants: Assessment of the risk factors', Vascular Health and Risk Management, vol. 7, no. 1, pp. 503-507. https://doi.org/10.2147/VHRM.S19645
Etemadi J, Rahbar K, Haghighi AN, Bagheri N, Falaknazi K, Ardalan MR et al. Renal artery stenosis in kidney transplants: Assessment of the risk factors. Vascular Health and Risk Management. 2011 Jan 1;7(1):503-507. https://doi.org/10.2147/VHRM.S19645
Etemadi, Jalal ; Rahbar, Khosro ; Haghighi, Ali Nobakht ; Bagheri, Nazila ; Falaknazi, Kianoosh ; Ardalan, Mohammad Reza ; Ghabili, Kamyar ; Mohajel Shoja, Mohammadali. / Renal artery stenosis in kidney transplants : Assessment of the risk factors. In: Vascular Health and Risk Management. 2011 ; Vol. 7, No. 1. pp. 503-507.
@article{c0f74c8c96f14ca8b264e89faee03a47,
title = "Renal artery stenosis in kidney transplants: Assessment of the risk factors",
abstract = "Background: Transplant renal artery stenosis (TRAS) is an important cause of hypertension and renal allograft dysfunction occurring in kidney transplant recipients. However, conflicting predisposing risk factors for TRAS have been reported in the literature. Objective: The aim of the present study was to assess the potential correlation between possible risk factors and TRAS in a group of living donor renal transplant recipients 1 year after the renal transplantation. Methods: We evaluated the presence of renal artery stenosis in 16 recipients who presented with refractory hypertension and/or allograft dysfunction 1 year after renal transplantation. Screening for TRAS was made by magnetic resonance angiography and diagnosis was confirmed by conventional renal angiography. Age, gender, history of acute rejection, plasma lipid profile, serum creatinine, blood urea nitrogen, serum uric acid, calcium phosphate (CaPO4) product, alkaline phosphatase, fasting blood sugar, hemoglobin, and albumin were compared between the TRAS and non-TRAS groups. Results: Of 16 kidney transplant recipients, TRAS was diagnosed in three patients (two men and one woman). High levels of calcium, phosphorous, CaPO4 product, and low-density lipoprotein (LDL) cholesterol were significantly correlated with the risk of TRAS 1 year after renal transplantation (P < 0.05). Serum level of uric acid tended to have a significant correlation (P = 0.051). Conclusion: Correlation between high CaPO4 product, LDL cholesterol, and perhaps uric acid and TRAS in living donor renal transplant recipients 1 year after renal transplantation might suggest the importance of early detection and tight control of these potential risk factors.",
keywords = "Atherosclerosis, Calcium phosphate product, Low density lipoprotein, Transplant renal artery stenosis, Uric acid",
author = "Jalal Etemadi and Khosro Rahbar and Haghighi, {Ali Nobakht} and Nazila Bagheri and Kianoosh Falaknazi and Ardalan, {Mohammad Reza} and Kamyar Ghabili and {Mohajel Shoja}, Mohammadali",
year = "2011",
month = "1",
day = "1",
doi = "10.2147/VHRM.S19645",
language = "English (US)",
volume = "7",
pages = "503--507",
journal = "Vascular Health and Risk Management",
issn = "1176-6344",
publisher = "Dove Medical Press Ltd.",
number = "1",

}

TY - JOUR

T1 - Renal artery stenosis in kidney transplants

T2 - Assessment of the risk factors

AU - Etemadi, Jalal

AU - Rahbar, Khosro

AU - Haghighi, Ali Nobakht

AU - Bagheri, Nazila

AU - Falaknazi, Kianoosh

AU - Ardalan, Mohammad Reza

AU - Ghabili, Kamyar

AU - Mohajel Shoja, Mohammadali

PY - 2011/1/1

Y1 - 2011/1/1

N2 - Background: Transplant renal artery stenosis (TRAS) is an important cause of hypertension and renal allograft dysfunction occurring in kidney transplant recipients. However, conflicting predisposing risk factors for TRAS have been reported in the literature. Objective: The aim of the present study was to assess the potential correlation between possible risk factors and TRAS in a group of living donor renal transplant recipients 1 year after the renal transplantation. Methods: We evaluated the presence of renal artery stenosis in 16 recipients who presented with refractory hypertension and/or allograft dysfunction 1 year after renal transplantation. Screening for TRAS was made by magnetic resonance angiography and diagnosis was confirmed by conventional renal angiography. Age, gender, history of acute rejection, plasma lipid profile, serum creatinine, blood urea nitrogen, serum uric acid, calcium phosphate (CaPO4) product, alkaline phosphatase, fasting blood sugar, hemoglobin, and albumin were compared between the TRAS and non-TRAS groups. Results: Of 16 kidney transplant recipients, TRAS was diagnosed in three patients (two men and one woman). High levels of calcium, phosphorous, CaPO4 product, and low-density lipoprotein (LDL) cholesterol were significantly correlated with the risk of TRAS 1 year after renal transplantation (P < 0.05). Serum level of uric acid tended to have a significant correlation (P = 0.051). Conclusion: Correlation between high CaPO4 product, LDL cholesterol, and perhaps uric acid and TRAS in living donor renal transplant recipients 1 year after renal transplantation might suggest the importance of early detection and tight control of these potential risk factors.

AB - Background: Transplant renal artery stenosis (TRAS) is an important cause of hypertension and renal allograft dysfunction occurring in kidney transplant recipients. However, conflicting predisposing risk factors for TRAS have been reported in the literature. Objective: The aim of the present study was to assess the potential correlation between possible risk factors and TRAS in a group of living donor renal transplant recipients 1 year after the renal transplantation. Methods: We evaluated the presence of renal artery stenosis in 16 recipients who presented with refractory hypertension and/or allograft dysfunction 1 year after renal transplantation. Screening for TRAS was made by magnetic resonance angiography and diagnosis was confirmed by conventional renal angiography. Age, gender, history of acute rejection, plasma lipid profile, serum creatinine, blood urea nitrogen, serum uric acid, calcium phosphate (CaPO4) product, alkaline phosphatase, fasting blood sugar, hemoglobin, and albumin were compared between the TRAS and non-TRAS groups. Results: Of 16 kidney transplant recipients, TRAS was diagnosed in three patients (two men and one woman). High levels of calcium, phosphorous, CaPO4 product, and low-density lipoprotein (LDL) cholesterol were significantly correlated with the risk of TRAS 1 year after renal transplantation (P < 0.05). Serum level of uric acid tended to have a significant correlation (P = 0.051). Conclusion: Correlation between high CaPO4 product, LDL cholesterol, and perhaps uric acid and TRAS in living donor renal transplant recipients 1 year after renal transplantation might suggest the importance of early detection and tight control of these potential risk factors.

KW - Atherosclerosis

KW - Calcium phosphate product

KW - Low density lipoprotein

KW - Transplant renal artery stenosis

KW - Uric acid

UR - http://www.scopus.com/inward/record.url?scp=84856054344&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84856054344&partnerID=8YFLogxK

U2 - 10.2147/VHRM.S19645

DO - 10.2147/VHRM.S19645

M3 - Article

VL - 7

SP - 503

EP - 507

JO - Vascular Health and Risk Management

JF - Vascular Health and Risk Management

SN - 1176-6344

IS - 1

ER -