The repair of potentially lethal damage (PLDR) in a gamma-irradiated human hybrid cell line (skin fibroblast × HeLa) and its tumourigenic segregant has been studied as a function of cell density at the time of irradiation and during the post-irradiation repair period. The data show that PLDR occurs in both non-confluent and confluent cultures of both cell lines. Furthermore, there is evidence that the extent of PLDR is dependent on cell density and that cell-cell contact may be an important factor in this regard.
- Cell density
- Human hybrid cells
- Potentially lethal damage repair
ASJC Scopus subject areas
- Radiological and Ultrasound Technology
- Radiology Nuclear Medicine and imaging