Replacing caloric beverages with water or diet beverages for weight loss in adults: Main results of the Choose Healthy Options Consciously Everyday (CHOICE) randomized clinical trial

Deborah F. Tate, Gabrielle Turner-McGrievy, Elizabeth Lyons, June Stevens, Karen Erickson, Kristen Polzien, Molly Diamond, Xiaoshan Wang, Barry Popkin

Research output: Contribution to journalArticle

193 Citations (Scopus)

Abstract

Background: Replacement of caloric beverages with noncaloric beverages may be a simple strategy for promoting modest weight reduction; however, the effectiveness of this strategy is not known. Objective: We compared the replacement of caloric beverages with water or diet beverages (DBs) as a method of weight loss over 6 mo in adults and attention controls (ACs). Design: Overweight and obese adults [n = 318; BMI (in kg/m2): 36.3 ± 5.9; 84% female; age (mean ± SD): 42 ± 10.7 y; 54% black] substituted noncaloric beverages (water or DBs) for caloric beverages (≥200 kcal/d) or made dietary changes of their choosing (AC) for 6 mo. Results: In an intent-to-treat analysis, a significant reduction in weight and waist circumference and an improvement in systolic blood pressure were observed from 0 to 6 mo. Mean (±SEM) weight losses at 6 mo were -2.5 ± 0.45% in the DB group, -2.03 ± 0.40% in the Water group, and -1.76 ± 0.35% in the AC group; there were no significant differences between groups. The chance of achieving a 5% weight loss at 6 mo was greater in the DB group than in the AC group (OR: 2.29; 95% CI: 1.05, 5.01; P = 0.04). A significant reduction in fasting glucose at 6 mo (P = 0.019) and improved hydration at 3 (P = 0.0017) and 6 (P = 0.049) mo was observed in the Water group relative to the AC group. In a combined analysis, participants assigned to beverage replacement were 2 times as likely to have achieved a 5% weight loss (OR: 2.07; 95% CI: 1.02, 4.22; P = 0.04) than were the AC participants. Conclusions: Replacement of caloric beverages with noncaloric beverages as a weight-loss strategy resulted in average weight losses of 2% to 2.5%. This strategy could have public health significance and is a simple, straightforward message. This trial was registered at clinicaltrials.gov as NCT01017783.

Original languageEnglish (US)
Pages (from-to)555-563
Number of pages9
JournalAmerican Journal of Clinical Nutrition
Volume95
Issue number3
DOIs
StatePublished - Mar 1 2012

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Reducing Diet
Beverages
Randomized Controlled Trials
Water
Weight Loss
Diet
Control Groups
Blood Pressure
Waist Circumference
Fasting

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Replacing caloric beverages with water or diet beverages for weight loss in adults : Main results of the Choose Healthy Options Consciously Everyday (CHOICE) randomized clinical trial. / Tate, Deborah F.; Turner-McGrievy, Gabrielle; Lyons, Elizabeth; Stevens, June; Erickson, Karen; Polzien, Kristen; Diamond, Molly; Wang, Xiaoshan; Popkin, Barry.

In: American Journal of Clinical Nutrition, Vol. 95, No. 3, 01.03.2012, p. 555-563.

Research output: Contribution to journalArticle

Tate, Deborah F. ; Turner-McGrievy, Gabrielle ; Lyons, Elizabeth ; Stevens, June ; Erickson, Karen ; Polzien, Kristen ; Diamond, Molly ; Wang, Xiaoshan ; Popkin, Barry. / Replacing caloric beverages with water or diet beverages for weight loss in adults : Main results of the Choose Healthy Options Consciously Everyday (CHOICE) randomized clinical trial. In: American Journal of Clinical Nutrition. 2012 ; Vol. 95, No. 3. pp. 555-563.
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T2 - Main results of the Choose Healthy Options Consciously Everyday (CHOICE) randomized clinical trial

AU - Tate, Deborah F.

AU - Turner-McGrievy, Gabrielle

AU - Lyons, Elizabeth

AU - Stevens, June

AU - Erickson, Karen

AU - Polzien, Kristen

AU - Diamond, Molly

AU - Wang, Xiaoshan

AU - Popkin, Barry

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N2 - Background: Replacement of caloric beverages with noncaloric beverages may be a simple strategy for promoting modest weight reduction; however, the effectiveness of this strategy is not known. Objective: We compared the replacement of caloric beverages with water or diet beverages (DBs) as a method of weight loss over 6 mo in adults and attention controls (ACs). Design: Overweight and obese adults [n = 318; BMI (in kg/m2): 36.3 ± 5.9; 84% female; age (mean ± SD): 42 ± 10.7 y; 54% black] substituted noncaloric beverages (water or DBs) for caloric beverages (≥200 kcal/d) or made dietary changes of their choosing (AC) for 6 mo. Results: In an intent-to-treat analysis, a significant reduction in weight and waist circumference and an improvement in systolic blood pressure were observed from 0 to 6 mo. Mean (±SEM) weight losses at 6 mo were -2.5 ± 0.45% in the DB group, -2.03 ± 0.40% in the Water group, and -1.76 ± 0.35% in the AC group; there were no significant differences between groups. The chance of achieving a 5% weight loss at 6 mo was greater in the DB group than in the AC group (OR: 2.29; 95% CI: 1.05, 5.01; P = 0.04). A significant reduction in fasting glucose at 6 mo (P = 0.019) and improved hydration at 3 (P = 0.0017) and 6 (P = 0.049) mo was observed in the Water group relative to the AC group. In a combined analysis, participants assigned to beverage replacement were 2 times as likely to have achieved a 5% weight loss (OR: 2.07; 95% CI: 1.02, 4.22; P = 0.04) than were the AC participants. Conclusions: Replacement of caloric beverages with noncaloric beverages as a weight-loss strategy resulted in average weight losses of 2% to 2.5%. This strategy could have public health significance and is a simple, straightforward message. This trial was registered at clinicaltrials.gov as NCT01017783.

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