Restriction and expansion of Ehrlichia strain diversity

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Ehrlichia are tick-borne gram negative, obligately intracellular bacteria. The 16S rRNA gene DNA sequences are highly conserved among strains of each Ehrlichia species. The 28-kDa/Map-1 outer membrane protein genes are highly diversified among strains of Ehrlichia chaffeensis and E. ruminantium, but are highly conserved among E. canis isolates. The diversity of the immunodominant proteins of E. chaffeensis and E. ruminantium in contrast with the conservation of the immunodominant proteins of E. canis suggests that E. chaffeensis and E. ruminantium face more host immune pressure than E. canis or that E. chaffeensis and E. ruminantium evolved earlier than E. canis and have diverged.

Original languageEnglish (US)
Pages (from-to)337-346
Number of pages10
JournalVeterinary Parasitology
Volume143
Issue number3-4
DOIs
StatePublished - Feb 28 2007

Fingerprint

Ehrlichia chaffeensis
Ehrlichia
Canis
strain differences
Ruminants
ruminants
outer membrane proteins
Ticks
rRNA Genes
ticks
Membrane Proteins
Proteins
genes
proteins
ribosomal RNA
Bacteria
nucleotide sequences
Pressure
bacteria
Genes

Keywords

  • Ehrlichia
  • Genetic variation
  • Outer membrane protein

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Parasitology
  • veterinary(all)

Cite this

Restriction and expansion of Ehrlichia strain diversity. / Yu, Xue jie; McBride, Jere; Walker, David.

In: Veterinary Parasitology, Vol. 143, No. 3-4, 28.02.2007, p. 337-346.

Research output: Contribution to journalArticle

@article{e3901ded40b04d5f8307919a99c49fb8,
title = "Restriction and expansion of Ehrlichia strain diversity",
abstract = "Ehrlichia are tick-borne gram negative, obligately intracellular bacteria. The 16S rRNA gene DNA sequences are highly conserved among strains of each Ehrlichia species. The 28-kDa/Map-1 outer membrane protein genes are highly diversified among strains of Ehrlichia chaffeensis and E. ruminantium, but are highly conserved among E. canis isolates. The diversity of the immunodominant proteins of E. chaffeensis and E. ruminantium in contrast with the conservation of the immunodominant proteins of E. canis suggests that E. chaffeensis and E. ruminantium face more host immune pressure than E. canis or that E. chaffeensis and E. ruminantium evolved earlier than E. canis and have diverged.",
keywords = "Ehrlichia, Genetic variation, Outer membrane protein",
author = "Yu, {Xue jie} and Jere McBride and David Walker",
year = "2007",
month = "2",
day = "28",
doi = "10.1016/j.vetpar.2006.08.027",
language = "English (US)",
volume = "143",
pages = "337--346",
journal = "Veterinary Parasitology: Regional Studies and Reports",
issn = "0304-4017",
publisher = "Elsevier",
number = "3-4",

}

TY - JOUR

T1 - Restriction and expansion of Ehrlichia strain diversity

AU - Yu, Xue jie

AU - McBride, Jere

AU - Walker, David

PY - 2007/2/28

Y1 - 2007/2/28

N2 - Ehrlichia are tick-borne gram negative, obligately intracellular bacteria. The 16S rRNA gene DNA sequences are highly conserved among strains of each Ehrlichia species. The 28-kDa/Map-1 outer membrane protein genes are highly diversified among strains of Ehrlichia chaffeensis and E. ruminantium, but are highly conserved among E. canis isolates. The diversity of the immunodominant proteins of E. chaffeensis and E. ruminantium in contrast with the conservation of the immunodominant proteins of E. canis suggests that E. chaffeensis and E. ruminantium face more host immune pressure than E. canis or that E. chaffeensis and E. ruminantium evolved earlier than E. canis and have diverged.

AB - Ehrlichia are tick-borne gram negative, obligately intracellular bacteria. The 16S rRNA gene DNA sequences are highly conserved among strains of each Ehrlichia species. The 28-kDa/Map-1 outer membrane protein genes are highly diversified among strains of Ehrlichia chaffeensis and E. ruminantium, but are highly conserved among E. canis isolates. The diversity of the immunodominant proteins of E. chaffeensis and E. ruminantium in contrast with the conservation of the immunodominant proteins of E. canis suggests that E. chaffeensis and E. ruminantium face more host immune pressure than E. canis or that E. chaffeensis and E. ruminantium evolved earlier than E. canis and have diverged.

KW - Ehrlichia

KW - Genetic variation

KW - Outer membrane protein

UR - http://www.scopus.com/inward/record.url?scp=33846226534&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846226534&partnerID=8YFLogxK

U2 - 10.1016/j.vetpar.2006.08.027

DO - 10.1016/j.vetpar.2006.08.027

M3 - Article

VL - 143

SP - 337

EP - 346

JO - Veterinary Parasitology: Regional Studies and Reports

JF - Veterinary Parasitology: Regional Studies and Reports

SN - 0304-4017

IS - 3-4

ER -