Resuscitation of severely burned military casualties: Fluid begets more fluid

Kevin K. Chung, Steven Wolf, Leopoldo C. Cancio, Ricardo Alvarado, John A. Jones, Jeffery McCorcle, Booker T. King, David J. Barillo, Evan M. Renz, Lorne H. Blackbourne

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

BACKGROUND: In November 2005, institution of a military-wide burn resuscitation guideline requested the documentation of the initial 24-hour resuscitation of severely burned military casualties on a burn flow sheet to provide continuity of care. The guidelines instruct the providers to calculate predicted 24-hour fluid requirements and initial fluid rate based on the American Burn Association Consensus recommendation of 2 (modified Brooke) mL·kg·% total body surface area (TBSA) to 4 (Parkland) mL·kg·%TBSA burn. The objective of this study was to evaluate the relationship between the estimated fluid volumes calculated, either by the Modified Brooke or the Parkland formulas, and actual volumes received. METHODS: From November 2005 to December 2008, 105 patients were globally evacuated with >20% TBSA burns, of whom 73 had burn flow sheets initiated. Of these, 58 had completed burn flow sheets. Total fluids administered in the first 24-hour period for each patient were recorded. Chart reviews were performed to extract demographic and clinical outcomes data. RESULTS: Of the 58, the modified Brooke formula was used in 31 patients (modified Brooke group) to estimate 24-hour fluid requirements and the Parkland formula was used in 21 (Parkland group). In six, 3 mL·kg·%TBSA was used and were excluded from analysis. No significant difference was detected between the two groups for age, %TBSA burned, inhalation injury, or Injury Severity Score. Actual 24-hour resuscitation in the modified Brooke group was significantly lower than in the Parkland group (16.9 L ± 6.0 L vs. 25.0 L ± 11.2 L, p = 0.003). A greater percentage of patients exceeded the Ivy index (250 mL/kg) in the Parkland group compared with the modified Brooke group (57% vs. 29%, p = 0.026). On average, those who had 24-hour fluid needs estimated by the modified Brooke formula received a 3.8 mL·kg·%TBSA ± 1.2 mL·kg·%TBSA resuscitation, whereas the Parkland group received a 5.9 mL·kg·%TBSA ± 1.1 mL·kg·%TBSA resuscitation (p < 0.0001). No differences in measured outcomes were detected between the two groups. On multivariate logistic regression, exceeding the Ivy index was an independent predictor of death (area under the curve [AUC], 0.807; CI, 0.66-0.95). CONCLUSION: In severely burned military casualties undergoing initial burn resuscitation, the modified Brooke formula resulted in significantly less 24-hour volumes without resulting in higher morbidity or mortality.

Original languageEnglish (US)
Pages (from-to)231-237
Number of pages7
JournalJournal of Trauma - Injury, Infection and Critical Care
Volume67
Issue number2
DOIs
StatePublished - Aug 1 2009
Externally publishedYes

Fingerprint

Body Surface Area
Resuscitation
Guidelines
Injury Severity Score
Continuity of Patient Care
Burns
Documentation
Inhalation
Area Under Curve
Age Groups
Logistic Models
Demography
Morbidity
Mortality
Wounds and Injuries

Keywords

  • Brooke
  • Burns
  • Casualties
  • Complications
  • Fluids
  • Formula
  • Military
  • Modified
  • Parkland
  • Resuscitation

ASJC Scopus subject areas

  • Surgery
  • Critical Care and Intensive Care Medicine

Cite this

Resuscitation of severely burned military casualties : Fluid begets more fluid. / Chung, Kevin K.; Wolf, Steven; Cancio, Leopoldo C.; Alvarado, Ricardo; Jones, John A.; McCorcle, Jeffery; King, Booker T.; Barillo, David J.; Renz, Evan M.; Blackbourne, Lorne H.

In: Journal of Trauma - Injury, Infection and Critical Care, Vol. 67, No. 2, 01.08.2009, p. 231-237.

Research output: Contribution to journalArticle

Chung, KK, Wolf, S, Cancio, LC, Alvarado, R, Jones, JA, McCorcle, J, King, BT, Barillo, DJ, Renz, EM & Blackbourne, LH 2009, 'Resuscitation of severely burned military casualties: Fluid begets more fluid', Journal of Trauma - Injury, Infection and Critical Care, vol. 67, no. 2, pp. 231-237. https://doi.org/10.1097/TA.0b013e3181ac68cf
Chung, Kevin K. ; Wolf, Steven ; Cancio, Leopoldo C. ; Alvarado, Ricardo ; Jones, John A. ; McCorcle, Jeffery ; King, Booker T. ; Barillo, David J. ; Renz, Evan M. ; Blackbourne, Lorne H. / Resuscitation of severely burned military casualties : Fluid begets more fluid. In: Journal of Trauma - Injury, Infection and Critical Care. 2009 ; Vol. 67, No. 2. pp. 231-237.
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abstract = "BACKGROUND: In November 2005, institution of a military-wide burn resuscitation guideline requested the documentation of the initial 24-hour resuscitation of severely burned military casualties on a burn flow sheet to provide continuity of care. The guidelines instruct the providers to calculate predicted 24-hour fluid requirements and initial fluid rate based on the American Burn Association Consensus recommendation of 2 (modified Brooke) mL·kg·{\%} total body surface area (TBSA) to 4 (Parkland) mL·kg·{\%}TBSA burn. The objective of this study was to evaluate the relationship between the estimated fluid volumes calculated, either by the Modified Brooke or the Parkland formulas, and actual volumes received. METHODS: From November 2005 to December 2008, 105 patients were globally evacuated with >20{\%} TBSA burns, of whom 73 had burn flow sheets initiated. Of these, 58 had completed burn flow sheets. Total fluids administered in the first 24-hour period for each patient were recorded. Chart reviews were performed to extract demographic and clinical outcomes data. RESULTS: Of the 58, the modified Brooke formula was used in 31 patients (modified Brooke group) to estimate 24-hour fluid requirements and the Parkland formula was used in 21 (Parkland group). In six, 3 mL·kg·{\%}TBSA was used and were excluded from analysis. No significant difference was detected between the two groups for age, {\%}TBSA burned, inhalation injury, or Injury Severity Score. Actual 24-hour resuscitation in the modified Brooke group was significantly lower than in the Parkland group (16.9 L ± 6.0 L vs. 25.0 L ± 11.2 L, p = 0.003). A greater percentage of patients exceeded the Ivy index (250 mL/kg) in the Parkland group compared with the modified Brooke group (57{\%} vs. 29{\%}, p = 0.026). On average, those who had 24-hour fluid needs estimated by the modified Brooke formula received a 3.8 mL·kg·{\%}TBSA ± 1.2 mL·kg·{\%}TBSA resuscitation, whereas the Parkland group received a 5.9 mL·kg·{\%}TBSA ± 1.1 mL·kg·{\%}TBSA resuscitation (p < 0.0001). No differences in measured outcomes were detected between the two groups. On multivariate logistic regression, exceeding the Ivy index was an independent predictor of death (area under the curve [AUC], 0.807; CI, 0.66-0.95). CONCLUSION: In severely burned military casualties undergoing initial burn resuscitation, the modified Brooke formula resulted in significantly less 24-hour volumes without resulting in higher morbidity or mortality.",
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T1 - Resuscitation of severely burned military casualties

T2 - Fluid begets more fluid

AU - Chung, Kevin K.

AU - Wolf, Steven

AU - Cancio, Leopoldo C.

AU - Alvarado, Ricardo

AU - Jones, John A.

AU - McCorcle, Jeffery

AU - King, Booker T.

AU - Barillo, David J.

AU - Renz, Evan M.

AU - Blackbourne, Lorne H.

PY - 2009/8/1

Y1 - 2009/8/1

N2 - BACKGROUND: In November 2005, institution of a military-wide burn resuscitation guideline requested the documentation of the initial 24-hour resuscitation of severely burned military casualties on a burn flow sheet to provide continuity of care. The guidelines instruct the providers to calculate predicted 24-hour fluid requirements and initial fluid rate based on the American Burn Association Consensus recommendation of 2 (modified Brooke) mL·kg·% total body surface area (TBSA) to 4 (Parkland) mL·kg·%TBSA burn. The objective of this study was to evaluate the relationship between the estimated fluid volumes calculated, either by the Modified Brooke or the Parkland formulas, and actual volumes received. METHODS: From November 2005 to December 2008, 105 patients were globally evacuated with >20% TBSA burns, of whom 73 had burn flow sheets initiated. Of these, 58 had completed burn flow sheets. Total fluids administered in the first 24-hour period for each patient were recorded. Chart reviews were performed to extract demographic and clinical outcomes data. RESULTS: Of the 58, the modified Brooke formula was used in 31 patients (modified Brooke group) to estimate 24-hour fluid requirements and the Parkland formula was used in 21 (Parkland group). In six, 3 mL·kg·%TBSA was used and were excluded from analysis. No significant difference was detected between the two groups for age, %TBSA burned, inhalation injury, or Injury Severity Score. Actual 24-hour resuscitation in the modified Brooke group was significantly lower than in the Parkland group (16.9 L ± 6.0 L vs. 25.0 L ± 11.2 L, p = 0.003). A greater percentage of patients exceeded the Ivy index (250 mL/kg) in the Parkland group compared with the modified Brooke group (57% vs. 29%, p = 0.026). On average, those who had 24-hour fluid needs estimated by the modified Brooke formula received a 3.8 mL·kg·%TBSA ± 1.2 mL·kg·%TBSA resuscitation, whereas the Parkland group received a 5.9 mL·kg·%TBSA ± 1.1 mL·kg·%TBSA resuscitation (p < 0.0001). No differences in measured outcomes were detected between the two groups. On multivariate logistic regression, exceeding the Ivy index was an independent predictor of death (area under the curve [AUC], 0.807; CI, 0.66-0.95). CONCLUSION: In severely burned military casualties undergoing initial burn resuscitation, the modified Brooke formula resulted in significantly less 24-hour volumes without resulting in higher morbidity or mortality.

AB - BACKGROUND: In November 2005, institution of a military-wide burn resuscitation guideline requested the documentation of the initial 24-hour resuscitation of severely burned military casualties on a burn flow sheet to provide continuity of care. The guidelines instruct the providers to calculate predicted 24-hour fluid requirements and initial fluid rate based on the American Burn Association Consensus recommendation of 2 (modified Brooke) mL·kg·% total body surface area (TBSA) to 4 (Parkland) mL·kg·%TBSA burn. The objective of this study was to evaluate the relationship between the estimated fluid volumes calculated, either by the Modified Brooke or the Parkland formulas, and actual volumes received. METHODS: From November 2005 to December 2008, 105 patients were globally evacuated with >20% TBSA burns, of whom 73 had burn flow sheets initiated. Of these, 58 had completed burn flow sheets. Total fluids administered in the first 24-hour period for each patient were recorded. Chart reviews were performed to extract demographic and clinical outcomes data. RESULTS: Of the 58, the modified Brooke formula was used in 31 patients (modified Brooke group) to estimate 24-hour fluid requirements and the Parkland formula was used in 21 (Parkland group). In six, 3 mL·kg·%TBSA was used and were excluded from analysis. No significant difference was detected between the two groups for age, %TBSA burned, inhalation injury, or Injury Severity Score. Actual 24-hour resuscitation in the modified Brooke group was significantly lower than in the Parkland group (16.9 L ± 6.0 L vs. 25.0 L ± 11.2 L, p = 0.003). A greater percentage of patients exceeded the Ivy index (250 mL/kg) in the Parkland group compared with the modified Brooke group (57% vs. 29%, p = 0.026). On average, those who had 24-hour fluid needs estimated by the modified Brooke formula received a 3.8 mL·kg·%TBSA ± 1.2 mL·kg·%TBSA resuscitation, whereas the Parkland group received a 5.9 mL·kg·%TBSA ± 1.1 mL·kg·%TBSA resuscitation (p < 0.0001). No differences in measured outcomes were detected between the two groups. On multivariate logistic regression, exceeding the Ivy index was an independent predictor of death (area under the curve [AUC], 0.807; CI, 0.66-0.95). CONCLUSION: In severely burned military casualties undergoing initial burn resuscitation, the modified Brooke formula resulted in significantly less 24-hour volumes without resulting in higher morbidity or mortality.

KW - Brooke

KW - Burns

KW - Casualties

KW - Complications

KW - Fluids

KW - Formula

KW - Military

KW - Modified

KW - Parkland

KW - Resuscitation

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