TY - JOUR
T1 - Retraction Note
T2 - Target receptor identification and subsequent treatment of resected brain tumors with encapsulated and engineered allogeneic stem cells (Nature Communications, (2022), 13, 1, (2810), 10.1038/s41467-022-30558-3)
AU - Bhere, Deepak
AU - Choi, Sung Hugh
AU - van de Donk, Pim
AU - Hope, David
AU - Gortzak, Kiki
AU - Kunnummal, Amina
AU - Khalsa, Jasneet
AU - Lechtich, Esther Revai
AU - Reinshagen, Clemens
AU - Leon, Victoria
AU - Nissar, Nabil
AU - Bi, Wenya Linda
AU - Feng, Cheng
AU - Li, Hongbin
AU - Zhang, Yu Shrike
AU - Liang, Steven H.
AU - Vasdev, Neil
AU - Essayed, Walid Ibn
AU - Quevedo, Pablo Valdes
AU - Golby, Alexandra
AU - Banouni, Naima
AU - Palagina, Anna
AU - Abdi, Reza
AU - Fury, Brian
AU - Smirnakis, Stelios
AU - Lowe, Alarice
AU - Reeve, Brock
AU - Hiller, Arthur
AU - Chiocca, E. Antonio
AU - Prestwich, Glenn
AU - Wakimoto, Hiroaki
AU - Bauer, Gerhard
AU - Shah, Khalid
N1 - Publisher Copyright:
© The Author(s) 2025.
PY - 2025/12
Y1 - 2025/12
N2 - Retraction to: Nature Communicationshttps://doi.org/10.1038/s41467-022-30558-3, published online 19 May 2022 The authors have retracted this article. After publication, concerns were raised regarding highly similar images between the figures presented in this article and a number of other sources, specifically: Fig. 1e GBM8 DR5 image appears highly similar to Fig. 1 Tu+Met Casp-1 in ref. 1; Fig. 1e GBM18 DR4 image appears highly similar to Fig. 3b HNSSC (PD) in ref. 1; Fig. 1f GBM31R mCherry image appears highly similar to Fig. 5f AGFP+MSC-GFP mCherry image in ref. 2; Fig. 1f GBM8 DR5 image appears highly similar to the BCHE Antibody image on the FisherScientific website ref. 3; Fig. 1f GBM8 DR4 image appears highly similar to Fig. 5c in ref. 4; Fig. S2a both images appear highly similar to human bone-derived mesenchymal stem cell images on the ScienCell website ref. 5; Fig. S4b Brain Untreated and EnMSC-Bif50 Week 2 images appear highly similar to Fig. 4c AZD9291 15 and 30 mg/kg in ref. 6, respectively; Fig. S4b Lung and Kidney EnMSC-Bif500 Week 4 and 8 images appear highly similar to Fig. 8a Lung (HA-VES7/DOX and DOX-Sol) and Kidney (HA-VES4/DOX and HA-VES12/DOX) images in ref. 7; Fig. S4b Brain EnMSC-Bif500 Week 8 image appears highly similar to Fig. 6a middle image in ref. 8; Fig. S4b Lung Untreated image appears highly similar to Fig. 2a Naturally aging group Lung image in ref. 9; Fig. S4b Lung EnMSC-Bif50 Week 2 image appears highly similar to Fig. 4 Lung WT image in ref. 10; Fig. S5a EnMSC-GFP Day 1, EnMSC-Bif Day 42, and EnMSC-Bif+GCV Day 1 images appear highly similar to Fig. 6e d7 and d15 A172-S TRAIL images in ref. 11. Fig. 1e GBM8 DR5 image appears highly similar to Fig. 1 Tu+Met Casp-1 in ref. 1; Fig. 1e GBM18 DR4 image appears highly similar to Fig. 3b HNSSC (PD) in ref. 1; Fig. 1f GBM31R mCherry image appears highly similar to Fig. 5f AGFP+MSC-GFP mCherry image in ref. 2; Fig. 1f GBM8 DR5 image appears highly similar to the BCHE Antibody image on the FisherScientific website ref. 3; Fig. 1f GBM8 DR4 image appears highly similar to Fig. 5c in ref. 4; Fig. S2a both images appear highly similar to human bone-derived mesenchymal stem cell images on the ScienCell website ref. 5; Fig. S4b Brain Untreated and EnMSC-Bif50 Week 2 images appear highly similar to Fig. 4c AZD9291 15 and 30 mg/kg in ref. 6, respectively; Fig. S4b Lung and Kidney EnMSC-Bif500 Week 4 and 8 images appear highly similar to Fig. 8a Lung (HA-VES7/DOX and DOX-Sol) and Kidney (HA-VES4/DOX and HA-VES12/DOX) images in ref. 7; Fig. S4b Brain EnMSC-Bif500 Week 8 image appears highly similar to Fig. 6a middle image in ref. 8; Fig. S4b Lung Untreated image appears highly similar to Fig. 2a Naturally aging group Lung image in ref. 9; Fig. S4b Lung EnMSC-Bif50 Week 2 image appears highly similar to Fig. 4 Lung WT image in ref. 10; Fig. S5a EnMSC-GFP Day 1, EnMSC-Bif Day 42, and EnMSC-Bif+GCV Day 1 images appear highly similar to Fig. 6e d7 and d15 A172-S TRAIL images in ref. 11. The authors have reviewed the data and confirmed that the images were reused incorrectly and without appropriate references. Deepak Bhere, Pim van de Donk, Victoria Leon, Naima Banouni, Reza Abdi, Arthur Hiller, Glenn Prestwich, Hiroaki Wakimoto, and Khalid Shah agree to this retraction. The publisher has been unable to obtain the current email addresses for David Hope, Jasneet Khalsa, Esther Revai Lechtich, Hongbin Li, Walid Ibn Essayed, Pablo Valdes Quevedo, and Gerhard Bauer. None of the other authors have responded to any correspondence from the publisher about this retraction.
AB - Retraction to: Nature Communicationshttps://doi.org/10.1038/s41467-022-30558-3, published online 19 May 2022 The authors have retracted this article. After publication, concerns were raised regarding highly similar images between the figures presented in this article and a number of other sources, specifically: Fig. 1e GBM8 DR5 image appears highly similar to Fig. 1 Tu+Met Casp-1 in ref. 1; Fig. 1e GBM18 DR4 image appears highly similar to Fig. 3b HNSSC (PD) in ref. 1; Fig. 1f GBM31R mCherry image appears highly similar to Fig. 5f AGFP+MSC-GFP mCherry image in ref. 2; Fig. 1f GBM8 DR5 image appears highly similar to the BCHE Antibody image on the FisherScientific website ref. 3; Fig. 1f GBM8 DR4 image appears highly similar to Fig. 5c in ref. 4; Fig. S2a both images appear highly similar to human bone-derived mesenchymal stem cell images on the ScienCell website ref. 5; Fig. S4b Brain Untreated and EnMSC-Bif50 Week 2 images appear highly similar to Fig. 4c AZD9291 15 and 30 mg/kg in ref. 6, respectively; Fig. S4b Lung and Kidney EnMSC-Bif500 Week 4 and 8 images appear highly similar to Fig. 8a Lung (HA-VES7/DOX and DOX-Sol) and Kidney (HA-VES4/DOX and HA-VES12/DOX) images in ref. 7; Fig. S4b Brain EnMSC-Bif500 Week 8 image appears highly similar to Fig. 6a middle image in ref. 8; Fig. S4b Lung Untreated image appears highly similar to Fig. 2a Naturally aging group Lung image in ref. 9; Fig. S4b Lung EnMSC-Bif50 Week 2 image appears highly similar to Fig. 4 Lung WT image in ref. 10; Fig. S5a EnMSC-GFP Day 1, EnMSC-Bif Day 42, and EnMSC-Bif+GCV Day 1 images appear highly similar to Fig. 6e d7 and d15 A172-S TRAIL images in ref. 11. Fig. 1e GBM8 DR5 image appears highly similar to Fig. 1 Tu+Met Casp-1 in ref. 1; Fig. 1e GBM18 DR4 image appears highly similar to Fig. 3b HNSSC (PD) in ref. 1; Fig. 1f GBM31R mCherry image appears highly similar to Fig. 5f AGFP+MSC-GFP mCherry image in ref. 2; Fig. 1f GBM8 DR5 image appears highly similar to the BCHE Antibody image on the FisherScientific website ref. 3; Fig. 1f GBM8 DR4 image appears highly similar to Fig. 5c in ref. 4; Fig. S2a both images appear highly similar to human bone-derived mesenchymal stem cell images on the ScienCell website ref. 5; Fig. S4b Brain Untreated and EnMSC-Bif50 Week 2 images appear highly similar to Fig. 4c AZD9291 15 and 30 mg/kg in ref. 6, respectively; Fig. S4b Lung and Kidney EnMSC-Bif500 Week 4 and 8 images appear highly similar to Fig. 8a Lung (HA-VES7/DOX and DOX-Sol) and Kidney (HA-VES4/DOX and HA-VES12/DOX) images in ref. 7; Fig. S4b Brain EnMSC-Bif500 Week 8 image appears highly similar to Fig. 6a middle image in ref. 8; Fig. S4b Lung Untreated image appears highly similar to Fig. 2a Naturally aging group Lung image in ref. 9; Fig. S4b Lung EnMSC-Bif50 Week 2 image appears highly similar to Fig. 4 Lung WT image in ref. 10; Fig. S5a EnMSC-GFP Day 1, EnMSC-Bif Day 42, and EnMSC-Bif+GCV Day 1 images appear highly similar to Fig. 6e d7 and d15 A172-S TRAIL images in ref. 11. The authors have reviewed the data and confirmed that the images were reused incorrectly and without appropriate references. Deepak Bhere, Pim van de Donk, Victoria Leon, Naima Banouni, Reza Abdi, Arthur Hiller, Glenn Prestwich, Hiroaki Wakimoto, and Khalid Shah agree to this retraction. The publisher has been unable to obtain the current email addresses for David Hope, Jasneet Khalsa, Esther Revai Lechtich, Hongbin Li, Walid Ibn Essayed, Pablo Valdes Quevedo, and Gerhard Bauer. None of the other authors have responded to any correspondence from the publisher about this retraction.
UR - http://www.scopus.com/inward/record.url?scp=105000868774&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=105000868774&partnerID=8YFLogxK
U2 - 10.1038/s41467-025-57909-0
DO - 10.1038/s41467-025-57909-0
M3 - Comment/debate
C2 - 40118851
AN - SCOPUS:105000868774
SN - 2041-1723
VL - 16
JO - Nature communications
JF - Nature communications
IS - 1
M1 - 2803
ER -