TY - JOUR
T1 - Rheumatic mitral insufficiency in children. Course, prognosis and effect of mitral valve replacement
AU - Harris, Leonard C.
AU - Nghiem, Quang X.
AU - Schreiber, Melvyn H.
N1 - Funding Information:
* From the Departments of Pediatrics and Radiology, The University of Texas, This study was supported in part by Grant No. 5Tl-HE-55703 from the National from the Texas Heart and Bay Area Heart Associations. t John and Mary R. Markle Foundation Scholar in Academic Medicine.
PY - 1966/2
Y1 - 1966/2
N2 - When the heart is involved as a result of rheumatic fever in children, mitral insufficiency is the most common lesion. Significant mitral stenosis, though it does occur, is not common in this age group. Twenty-eight children with rheumatic mitral insufficiency were divided into 3 groups of severity according to symptoms and heart size. Cardiac volume index and cardiothoracic ratio were compared as indexes of heart size in these patients. The course and prognosis were studied in each group by using cardiac volume index, cardiothoracic ratio, electrocardiographic, phonocardiographic, hemodynamic and clinical data as parameters of severity. In severe cases the course is one of progressive deterioration with development of atrial fibrillation or left atrial and right ventricular hypertension, or both. This course was illustrated by 8 fatal cases, death occurring between 11.5 and 15.5 years of age. In 2 patients the mitral valve was replaced by a Starr-Edwards valve. The patients are surviving and well, 12 and 17 months later. Guides are suggested for the selection of patients with mitral insufficiency for mitral valve surgery.
AB - When the heart is involved as a result of rheumatic fever in children, mitral insufficiency is the most common lesion. Significant mitral stenosis, though it does occur, is not common in this age group. Twenty-eight children with rheumatic mitral insufficiency were divided into 3 groups of severity according to symptoms and heart size. Cardiac volume index and cardiothoracic ratio were compared as indexes of heart size in these patients. The course and prognosis were studied in each group by using cardiac volume index, cardiothoracic ratio, electrocardiographic, phonocardiographic, hemodynamic and clinical data as parameters of severity. In severe cases the course is one of progressive deterioration with development of atrial fibrillation or left atrial and right ventricular hypertension, or both. This course was illustrated by 8 fatal cases, death occurring between 11.5 and 15.5 years of age. In 2 patients the mitral valve was replaced by a Starr-Edwards valve. The patients are surviving and well, 12 and 17 months later. Guides are suggested for the selection of patients with mitral insufficiency for mitral valve surgery.
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U2 - 10.1016/0002-9149(66)90352-3
DO - 10.1016/0002-9149(66)90352-3
M3 - Article
C2 - 5948172
AN - SCOPUS:0013878944
SN - 0002-9149
VL - 17
SP - 194
EP - 202
JO - The American Journal of Cardiology
JF - The American Journal of Cardiology
IS - 2
ER -