Rhizopus osteomyelitis. A case report and review

Roger M. Echols, Daniel S. Selinger, Christian Hallowell, James S. Goodwin, Marilyn H. Duncan, Alice H. Cushing

Research output: Contribution to journalReview articlepeer-review

30 Scopus citations


Mucormycosis osteomyelitis has previously been described exclusively in association with contiguous infections of rhinocerebral mucormycosis. In a patient with corticosteroid-dependent neutropenia and anemia osteomyelitis of the femur developed caused by the Mucoraceae Rhizopus. Although a primary focus was not identified, we believe this infection was hematogenous in origin. Mitogen stimulation to phytohemagglutinin (PHA) of the patient's lymphocytes revealed depressed cellular immunity; however, there was specific response to Rhizopus extract. Treatment with systemic amphotericin B prevented further progression of the infection. A review of mucormycosis osteomyelitis is presented.

Original languageEnglish (US)
Pages (from-to)141-145
Number of pages5
JournalThe American Journal of Medicine
Issue number1
StatePublished - Jan 1979
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine


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