Rhizopus osteomyelitis. A case report and review

Roger M. Echols, Daniel S. Selinger, Christian Hallowell, James Goodwin, Marilyn H. Duncan, Alice H. Cushing

Research output: Contribution to journalArticle

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Abstract

Mucormycosis osteomyelitis has previously been described exclusively in association with contiguous infections of rhinocerebral mucormycosis. In a patient with corticosteroid-dependent neutropenia and anemia osteomyelitis of the femur developed caused by the Mucoraceae Rhizopus. Although a primary focus was not identified, we believe this infection was hematogenous in origin. Mitogen stimulation to phytohemagglutinin (PHA) of the patient's lymphocytes revealed depressed cellular immunity; however, there was specific response to Rhizopus extract. Treatment with systemic amphotericin B prevented further progression of the infection. A review of mucormycosis osteomyelitis is presented.

Original languageEnglish (US)
Pages (from-to)141-145
Number of pages5
JournalThe American Journal of Medicine
Volume66
Issue number1
DOIs
StatePublished - 1979
Externally publishedYes

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Mucormycosis
Rhizopus
Osteomyelitis
Infection
Phytohemagglutinins
Amphotericin B
Neutropenia
Mitogens
Cellular Immunity
Femur
Anemia
Adrenal Cortex Hormones
Lymphocytes
Therapeutics

ASJC Scopus subject areas

  • Nursing(all)

Cite this

Echols, R. M., Selinger, D. S., Hallowell, C., Goodwin, J., Duncan, M. H., & Cushing, A. H. (1979). Rhizopus osteomyelitis. A case report and review. The American Journal of Medicine, 66(1), 141-145. https://doi.org/10.1016/0002-9343(79)90505-9

Rhizopus osteomyelitis. A case report and review. / Echols, Roger M.; Selinger, Daniel S.; Hallowell, Christian; Goodwin, James; Duncan, Marilyn H.; Cushing, Alice H.

In: The American Journal of Medicine, Vol. 66, No. 1, 1979, p. 141-145.

Research output: Contribution to journalArticle

Echols, RM, Selinger, DS, Hallowell, C, Goodwin, J, Duncan, MH & Cushing, AH 1979, 'Rhizopus osteomyelitis. A case report and review', The American Journal of Medicine, vol. 66, no. 1, pp. 141-145. https://doi.org/10.1016/0002-9343(79)90505-9
Echols, Roger M. ; Selinger, Daniel S. ; Hallowell, Christian ; Goodwin, James ; Duncan, Marilyn H. ; Cushing, Alice H. / Rhizopus osteomyelitis. A case report and review. In: The American Journal of Medicine. 1979 ; Vol. 66, No. 1. pp. 141-145.
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