Rhizopus osteomyelitis. A case report and review

Roger M. Echols; Daniel S. Selinger; Christian Hallowell; James S. Goodwin; Marilyn H. Duncan; Alice H. Cushing

doi:10.1016/0002-9343(79)90505-9

Rhizopus osteomyelitis. A case report and review

Roger M. Echols, Daniel S. Selinger, Christian Hallowell, James S. Goodwin, Marilyn H. Duncan, Alice H. Cushing

Research output: Contribution to journal › Review article › peer-review

33 Scopus citations

Abstract

Mucormycosis osteomyelitis has previously been described exclusively in association with contiguous infections of rhinocerebral mucormycosis. In a patient with corticosteroid-dependent neutropenia and anemia osteomyelitis of the femur developed caused by the Mucoraceae Rhizopus. Although a primary focus was not identified, we believe this infection was hematogenous in origin. Mitogen stimulation to phytohemagglutinin (PHA) of the patient's lymphocytes revealed depressed cellular immunity; however, there was specific response to Rhizopus extract. Treatment with systemic amphotericin B prevented further progression of the infection. A review of mucormycosis osteomyelitis is presented.

Original language	English (US)
Pages (from-to)	141-145
Number of pages	5
Journal	The American Journal of Medicine
Volume	66
Issue number	1
DOIs	https://doi.org/10.1016/0002-9343(79)90505-9
State	Published - Jan 1979
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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title = "Rhizopus osteomyelitis. A case report and review",

abstract = "Mucormycosis osteomyelitis has previously been described exclusively in association with contiguous infections of rhinocerebral mucormycosis. In a patient with corticosteroid-dependent neutropenia and anemia osteomyelitis of the femur developed caused by the Mucoraceae Rhizopus. Although a primary focus was not identified, we believe this infection was hematogenous in origin. Mitogen stimulation to phytohemagglutinin (PHA) of the patient's lymphocytes revealed depressed cellular immunity; however, there was specific response to Rhizopus extract. Treatment with systemic amphotericin B prevented further progression of the infection. A review of mucormycosis osteomyelitis is presented.",

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AU - Echols, Roger M.

AU - Selinger, Daniel S.

AU - Hallowell, Christian

AU - Goodwin, James S.

AU - Duncan, Marilyn H.

AU - Cushing, Alice H.

PY - 1979/1

Y1 - 1979/1

N2 - Mucormycosis osteomyelitis has previously been described exclusively in association with contiguous infections of rhinocerebral mucormycosis. In a patient with corticosteroid-dependent neutropenia and anemia osteomyelitis of the femur developed caused by the Mucoraceae Rhizopus. Although a primary focus was not identified, we believe this infection was hematogenous in origin. Mitogen stimulation to phytohemagglutinin (PHA) of the patient's lymphocytes revealed depressed cellular immunity; however, there was specific response to Rhizopus extract. Treatment with systemic amphotericin B prevented further progression of the infection. A review of mucormycosis osteomyelitis is presented.

AB - Mucormycosis osteomyelitis has previously been described exclusively in association with contiguous infections of rhinocerebral mucormycosis. In a patient with corticosteroid-dependent neutropenia and anemia osteomyelitis of the femur developed caused by the Mucoraceae Rhizopus. Although a primary focus was not identified, we believe this infection was hematogenous in origin. Mitogen stimulation to phytohemagglutinin (PHA) of the patient's lymphocytes revealed depressed cellular immunity; however, there was specific response to Rhizopus extract. Treatment with systemic amphotericin B prevented further progression of the infection. A review of mucormycosis osteomyelitis is presented.

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Rhizopus osteomyelitis. A case report and review

Abstract

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