Rhythmic Interlimb Coordination Impairments and the Risk for Developing Mobility Limitations

Eric G. James, Suzanne G. Leveille, Jeffrey M. Hausdorff, Thomas Travison, David N. Kennedy, Katherine L. Tucker, Soham Al Snih al snih, Kyriakos Markides, Jonathan F. Bean

Research output: Contribution to journalArticle

Abstract

Background: The identification of novel rehabilitative impairments that are risk factors for mobility limitations may improve their prevention and treatment among older adults. We tested the hypothesis that impaired rhythmic interlimb ankle and shoulder coordination are risk factors for subsequent mobility limitations among older adults. Methods: We conducted a 1-year prospective cohort study of community-dwelling older adults (N = 99) aged 67 years and older who did not have mobility limitations (Short Physical Performance Battery score > 9) at baseline. Participants performed antiphase coordination of the right and left ankles or shoulders while paced by an auditory metronome. Using multivariable logistic regression, we determined odds ratios (ORs) for mobility limitations at 1-year follow-up as a function of coordination variability and asymmetry. Results: After adjusting for age, sex, body mass index, Mini-Mental State Examination score, number of chronic conditions, and baseline Short Physical Performance Battery score, ORs were significant for developing mobility limitations based on a 1 SD difference in the variability of ankle (OR = 1.88; 95% confidence interval [CI]: 1.16-3.05) and shoulder (OR = 1.96; 95% CI: 1.17-3.29) coordination. ORs were significant for asymmetry of shoulder (OR = 2.11; 95% CI: 1.25-3.57), but not ankle (OR = 0.95; 95% CI: 0.59-1.55) coordination. Similar results were found in unadjusted analyses. Conclusions: The results support our hypothesis that impaired interlimb ankle and shoulder coordination are risk factors for the development of mobility limitations. Future work is needed to further examine the peripheral and central mechanisms underlying this relationship and to test whether enhancing coordination alters mobility limitations.

Original languageEnglish (US)
Pages (from-to)1143-1148
Number of pages6
JournalJournals of Gerontology - Series A Biological Sciences and Medical Sciences
Volume72
Issue number8
DOIs
StatePublished - Aug 1 2017

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Mobility Limitation
Ataxia
Odds Ratio
Ankle
Confidence Intervals
Independent Living
Body Mass Index
Cohort Studies
Logistic Models
Prospective Studies

Keywords

  • Aging
  • Coordination
  • Interlimb
  • Mobility
  • Risk

ASJC Scopus subject areas

  • Aging
  • Geriatrics and Gerontology

Cite this

James, E. G., Leveille, S. G., Hausdorff, J. M., Travison, T., Kennedy, D. N., Tucker, K. L., ... Bean, J. F. (2017). Rhythmic Interlimb Coordination Impairments and the Risk for Developing Mobility Limitations. Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 72(8), 1143-1148. https://doi.org/10.1093/gerona/glw236

Rhythmic Interlimb Coordination Impairments and the Risk for Developing Mobility Limitations. / James, Eric G.; Leveille, Suzanne G.; Hausdorff, Jeffrey M.; Travison, Thomas; Kennedy, David N.; Tucker, Katherine L.; Al Snih al snih, Soham; Markides, Kyriakos; Bean, Jonathan F.

In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences, Vol. 72, No. 8, 01.08.2017, p. 1143-1148.

Research output: Contribution to journalArticle

James, Eric G. ; Leveille, Suzanne G. ; Hausdorff, Jeffrey M. ; Travison, Thomas ; Kennedy, David N. ; Tucker, Katherine L. ; Al Snih al snih, Soham ; Markides, Kyriakos ; Bean, Jonathan F. / Rhythmic Interlimb Coordination Impairments and the Risk for Developing Mobility Limitations. In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 2017 ; Vol. 72, No. 8. pp. 1143-1148.
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