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Ribosome-Targeting Antibiotics: Modes of Action, Mechanisms of Resistance, and Implications for Drug Design
Jinzhong Lin
, Dejian Zhou
, Thomas A. Steitz
, Yury S. Polikanov
,
Matthieu G. Gagnon
Microbiology And Immunology
Research output
:
Contribution to journal
›
Review article
›
peer-review
271
Scopus citations
Overview
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Dive into the research topics of 'Ribosome-Targeting Antibiotics: Modes of Action, Mechanisms of Resistance, and Implications for Drug Design'. Together they form a unique fingerprint.
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Keyphrases
Drug Design
100%
Mechanism of Action
100%
Resistance Mechanisms
100%
Antibiotic Modes of Action
100%
Protein Synthesis
50%
Antibiotics
50%
Therapeutic Agents
50%
Structure Function
50%
Microbes
50%
Recent Advances
50%
Bacterial Infection
50%
Mode of Action
50%
Effective Antibiotics
50%
Antimicrobial
50%
Pathogenic Bacteria
50%
Proteinase Inhibitor
50%
Difficult-to-treat
50%
Multidrug-resistant Pathogens
50%
Public Healthcare
50%
Ribosome Inhibitors
50%
Major Resistance
50%
Assisted Design
50%
Pharmacology, Toxicology and Pharmaceutical Science
Antibiotics
100%
Drug Development
100%
Infection
33%
Infectious Agent
33%
Bacterial Infection
33%
Antiinfective Agent
33%
Protein Synthesis Inhibitor
33%