Risks of Immunotherapy with Insect Venom

J. Andrew Grant

Research output: Contribution to journalLetterpeer-review

2 Scopus citations


To the Editor: The study by Hunt et al.1 should settle the question of the proper management of patients with insect hypersensitivity. By the use of a single-blind protocol, intentional insect-sting challenge and monitoring of IgG blocking antibody response, the authors unequivocally demonstrate the effectiveness of venom-sac extracts over whole-body extracts. This study analyzed patients with allergic reactions to honeybee and yellow-jacket stings, whereas the principal culprit in regions of the southern United States is the paper nest wasp of the genus polistes.2 In a small group of patients, we have shown that polistes venom is also effective in diagnosing. No extract is available for articles shorter than 400 words.

Original languageEnglish (US)
Pages (from-to)565
Number of pages1
JournalNew England Journal of Medicine
Issue number10
StatePublished - Mar 8 1979

ASJC Scopus subject areas

  • General Medicine


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