RNA virus infections and their effect on host alternative splicing

Sapna Sehrawat, Mariano A. Garcia-Blanco

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

It is evident that viral infection dramatically alters host gene expression, and these alterations have both pro- and anti-viral functions. While the effects of viral infection on transcription and translation have been comprehensively reviewed, less attention has been paid to the impact on alternative splicing of pre-messenger RNAs. Here we review salient examples of how viral infection leads to changes in alternative splicing and discuss how these changes impact infection.

Original languageEnglish (US)
Article number105503
JournalAntiviral research
Volume210
DOIs
StatePublished - Feb 2023

Keywords

  • Alternative splicing
  • Post-transcriptional modification
  • Pre-messenger RNA
  • RNA virus
  • Viral infection

ASJC Scopus subject areas

  • Pharmacology
  • Virology

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