ROLE OF ANIMAL EXPERIMENTS IN RISK ESTIMATES.

R. L. Ullrich

Research output: Contribution to journalConference article

Abstract

Estimates of risk for low radiation doses and protracted exposures cannot be made directly from available data but must be derived by extrapolation from observation at high doses, based on models of dose and dose-rate relationships. Dose response and dose-rate data that are sufficient to develop and test such models were obtained from studies in animals. The data on tumor induction after low linear energy transfer (LET) radiation for various experimental systems has clearly shown that the dose response varies greatly from tissue to tissue. Because of this, no single dose response model is adequate to describe all the data.

Original languageEnglish (US)
Number of pages1
JournalTransactions of the American Nuclear Society
Volume46
StatePublished - Dec 1 1984

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ASJC Scopus subject areas

  • Energy Engineering and Power Technology
  • Nuclear Energy and Engineering
  • Industrial and Manufacturing Engineering

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