Abstract
The optimal laboratory evaluation for the early detection of liver metastases from colorectal cancer is controversial. This investigation was undertaken to compare the efficacy of liver function tests (LFTs) with that of carcinoembryonic antigen (CEA) levels for the early detection of liver metastases. Patients who developed liver metastases after potentially curative resections of adenocarcinoma of the colorectum between 1974 and 1988 were reviewed. The following laboratory tests were serially evaluated during the follow-up period: CEA., alkaline phosphatase (AP), serum glutamic oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT), and lactic dehydrogenase (LDH). These values were retrospectively assessed from the time of documented liver metastases to identify which lab value (s) were elevated initially. Ninety-two patients were available for study. Average time for the occurrence of liver metastases was 20 months (range, 3-72 months). The incidence of elevation of individual tests at the time of suspicion of liver metastasis was: CEA, 94.6 percent (P
| Original language | English (US) |
|---|---|
| Pages (from-to) | 794-797 |
| Number of pages | 4 |
| Journal | Diseases of the Colon and Rectum |
| Volume | 34 |
| Issue number | 9 |
| DOIs | |
| State | Published - Sep 1991 |
| Externally published | Yes |
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Keywords
- Cancer surveillance
- Carcinoembryonic antigen
- Colorectal carcinoma
- Liver function tests
- Liver metastases
ASJC Scopus subject areas
- Gastroenterology
Cite this
Role of carcinoembryonic antigen and liver function tests in the detection of recurrent colorectal carcinoma. / Rocklin, Marc S.; Senagore, Anthony J.; Talbott, Timothy M.
In: Diseases of the Colon and Rectum, Vol. 34, No. 9, 09.1991, p. 794-797.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Role of carcinoembryonic antigen and liver function tests in the detection of recurrent colorectal carcinoma
AU - Rocklin, Marc S.
AU - Senagore, Anthony J.
AU - Talbott, Timothy M.
PY - 1991/9
Y1 - 1991/9
N2 - The optimal laboratory evaluation for the early detection of liver metastases from colorectal cancer is controversial. This investigation was undertaken to compare the efficacy of liver function tests (LFTs) with that of carcinoembryonic antigen (CEA) levels for the early detection of liver metastases. Patients who developed liver metastases after potentially curative resections of adenocarcinoma of the colorectum between 1974 and 1988 were reviewed. The following laboratory tests were serially evaluated during the follow-up period: CEA., alkaline phosphatase (AP), serum glutamic oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT), and lactic dehydrogenase (LDH). These values were retrospectively assessed from the time of documented liver metastases to identify which lab value (s) were elevated initially. Ninety-two patients were available for study. Average time for the occurrence of liver metastases was 20 months (range, 3-72 months). The incidence of elevation of individual tests at the time of suspicion of liver metastasis was: CEA, 94.6 percent (P
AB - The optimal laboratory evaluation for the early detection of liver metastases from colorectal cancer is controversial. This investigation was undertaken to compare the efficacy of liver function tests (LFTs) with that of carcinoembryonic antigen (CEA) levels for the early detection of liver metastases. Patients who developed liver metastases after potentially curative resections of adenocarcinoma of the colorectum between 1974 and 1988 were reviewed. The following laboratory tests were serially evaluated during the follow-up period: CEA., alkaline phosphatase (AP), serum glutamic oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT), and lactic dehydrogenase (LDH). These values were retrospectively assessed from the time of documented liver metastases to identify which lab value (s) were elevated initially. Ninety-two patients were available for study. Average time for the occurrence of liver metastases was 20 months (range, 3-72 months). The incidence of elevation of individual tests at the time of suspicion of liver metastasis was: CEA, 94.6 percent (P
KW - Cancer surveillance
KW - Carcinoembryonic antigen
KW - Colorectal carcinoma
KW - Liver function tests
KW - Liver metastases
UR - http://www.scopus.com/inward/record.url?scp=0025949858&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025949858&partnerID=8YFLogxK
U2 - 10.1007/BF02051073
DO - 10.1007/BF02051073
M3 - Article
C2 - 1914746
AN - SCOPUS:0025949858
VL - 34
SP - 794
EP - 797
JO - Diseases of the Colon and Rectum
JF - Diseases of the Colon and Rectum
SN - 0012-3706
IS - 9
ER -