Role of non-coding RNAs in physiological and pathological angiogenesis

Nihay Laham-Karam; Isidore Mushimiyimana; Krista Hokkanen; Seppo Ylä-Herttuala

doi:10.1016/j.cophys.2023.100690

Role of non-coding RNAs in physiological and pathological angiogenesis

Nihay Laham-Karam
, Isidore Mushimiyimana
, Krista Hokkanen
, Seppo Ylä-Herttuala

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

Angiogenesis, the process of building new vessels, is important in physiology. In addition, it is involved in different pathologies, including cancers, ischemia, macular degeneration and inflammatory bowel disease. The regulation of angiogenesis is multifaceted and according to recent data includes transcriptional modulation by enhancers and non-coding RNAs as well as post-transcriptional regulation by microRNAs. In this review, we highlight recent findings in this field that relate both to physiological and pathological angiogenesis and discuss the effects on key angiogenic factors.

Original language	English (US)
Article number	100690
Journal	Current Opinion in Physiology
Volume	35
DOIs	https://doi.org/10.1016/j.cophys.2023.100690
State	Published - Oct 2023
Externally published	Yes

ASJC Scopus subject areas

Physiology
Physiology (medical)

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10.1016/j.cophys.2023.100690

Cite this

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title = "Role of non-coding RNAs in physiological and pathological angiogenesis",

abstract = "Angiogenesis, the process of building new vessels, is important in physiology. In addition, it is involved in different pathologies, including cancers, ischemia, macular degeneration and inflammatory bowel disease. The regulation of angiogenesis is multifaceted and according to recent data includes transcriptional modulation by enhancers and non-coding RNAs as well as post-transcriptional regulation by microRNAs. In this review, we highlight recent findings in this field that relate both to physiological and pathological angiogenesis and discuss the effects on key angiogenic factors.",

author = "Nihay Laham-Karam and Isidore Mushimiyimana and Krista Hokkanen and Seppo Yl{\"a}-Herttuala",

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language = "English (US)",

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AU - Laham-Karam, Nihay

AU - Mushimiyimana, Isidore

AU - Hokkanen, Krista

AU - Ylä-Herttuala, Seppo

PY - 2023/10

Y1 - 2023/10

N2 - Angiogenesis, the process of building new vessels, is important in physiology. In addition, it is involved in different pathologies, including cancers, ischemia, macular degeneration and inflammatory bowel disease. The regulation of angiogenesis is multifaceted and according to recent data includes transcriptional modulation by enhancers and non-coding RNAs as well as post-transcriptional regulation by microRNAs. In this review, we highlight recent findings in this field that relate both to physiological and pathological angiogenesis and discuss the effects on key angiogenic factors.

AB - Angiogenesis, the process of building new vessels, is important in physiology. In addition, it is involved in different pathologies, including cancers, ischemia, macular degeneration and inflammatory bowel disease. The regulation of angiogenesis is multifaceted and according to recent data includes transcriptional modulation by enhancers and non-coding RNAs as well as post-transcriptional regulation by microRNAs. In this review, we highlight recent findings in this field that relate both to physiological and pathological angiogenesis and discuss the effects on key angiogenic factors.

UR - https://www.scopus.com/pages/publications/85163349190

UR - https://www.scopus.com/pages/publications/85163349190#tab=citedBy

U2 - 10.1016/j.cophys.2023.100690

DO - 10.1016/j.cophys.2023.100690

M3 - Review article

AN - SCOPUS:85163349190

SN - 2468-8681

VL - 35

JO - Current Opinion in Physiology

JF - Current Opinion in Physiology

M1 - 100690

ER -

Role of non-coding RNAs in physiological and pathological angiogenesis

Abstract

ASJC Scopus subject areas

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