TY - JOUR
T1 - Role of non-coding RNAs in physiological and pathological angiogenesis
AU - Laham-Karam, Nihay
AU - Mushimiyimana, Isidore
AU - Hokkanen, Krista
AU - Ylä-Herttuala, Seppo
N1 - Publisher Copyright:
© 2023 The Author(s)
PY - 2023/10
Y1 - 2023/10
N2 - Angiogenesis, the process of building new vessels, is important in physiology. In addition, it is involved in different pathologies, including cancers, ischemia, macular degeneration and inflammatory bowel disease. The regulation of angiogenesis is multifaceted and according to recent data includes transcriptional modulation by enhancers and non-coding RNAs as well as post-transcriptional regulation by microRNAs. In this review, we highlight recent findings in this field that relate both to physiological and pathological angiogenesis and discuss the effects on key angiogenic factors.
AB - Angiogenesis, the process of building new vessels, is important in physiology. In addition, it is involved in different pathologies, including cancers, ischemia, macular degeneration and inflammatory bowel disease. The regulation of angiogenesis is multifaceted and according to recent data includes transcriptional modulation by enhancers and non-coding RNAs as well as post-transcriptional regulation by microRNAs. In this review, we highlight recent findings in this field that relate both to physiological and pathological angiogenesis and discuss the effects on key angiogenic factors.
UR - https://www.scopus.com/pages/publications/85163349190
UR - https://www.scopus.com/inward/citedby.url?scp=85163349190&partnerID=8YFLogxK
U2 - 10.1016/j.cophys.2023.100690
DO - 10.1016/j.cophys.2023.100690
M3 - Review article
AN - SCOPUS:85163349190
SN - 2468-8681
VL - 35
JO - Current Opinion in Physiology
JF - Current Opinion in Physiology
M1 - 100690
ER -