Role of viruses in middle-ear disease

Tasnee Chonmaitree

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Taken together, there is ample evidence suggesting a role for viruses in the pathogenesis of OM. This evidence comes from numerous studies performed in animals and in vitro cell cultures, as well as in adults and children with URI and OM. Viruses induce host immune and inflammatory responses that result in pathology of the ET and the middle ear, and predispose the host in various ways to secondary bacterial infection. A suggested mechanism for the pathogenesis of OM following respiratory viral infection is presented in FIGURE 1.

Original languageEnglish (US)
Pages (from-to)143-157
Number of pages15
JournalAnnals of the New York Academy of Sciences
Volume830
DOIs
StatePublished - Dec 29 1997

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Ear Diseases
Middle Ear
Viruses
Pathology
Virus Diseases
Coinfection
Cell culture
Bacterial Infections
Respiratory Tract Infections
Animals
Cell Culture Techniques
Virus
Infection
In Vitro Techniques
Cells

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Role of viruses in middle-ear disease. / Chonmaitree, Tasnee.

In: Annals of the New York Academy of Sciences, Vol. 830, 29.12.1997, p. 143-157.

Research output: Contribution to journalArticle

Chonmaitree, Tasnee. / Role of viruses in middle-ear disease. In: Annals of the New York Academy of Sciences. 1997 ; Vol. 830. pp. 143-157.
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