ROS Signalling of inflammatory cytokines during trypanosoma cruzi infection

Shivali Gupta, Monisha Dhiman, Jian jun Wen, Nisha Garg

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Inflammation is a host defence activated by exogenous (e.g. pathogen-derived, pollutants) or endogenous (e.g. reactive oxygen species-ROS) danger signals. Mostly, endogenous molecules (or their derivatives) have well-defined intracellular function but become danger signal when released or exposed following stress or injury. In this review, we discuss the potential role of ROS in chronic evolution of inflammatory cardiovascular diseases, using our experiences working on chagasic cardiomyopathy as a focus-point.

Original languageEnglish (US)
Pages (from-to)153-170
Number of pages18
JournalAdvances in Parasitology
Volume76
DOIs
StatePublished - 2011

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Trypanosoma cruzi
Cardiomyopathies
Reactive Oxygen Species
Cardiovascular Diseases
Cytokines
Inflammation
Wounds and Injuries
Infection

Keywords

  • Chagas
  • Cytokines
  • Inflammation
  • Oxidative stress
  • ROS
  • Trypanosoma cruzi

ASJC Scopus subject areas

  • Parasitology

Cite this

ROS Signalling of inflammatory cytokines during trypanosoma cruzi infection. / Gupta, Shivali; Dhiman, Monisha; Wen, Jian jun; Garg, Nisha.

In: Advances in Parasitology, Vol. 76, 2011, p. 153-170.

Research output: Contribution to journalArticle

Gupta, Shivali ; Dhiman, Monisha ; Wen, Jian jun ; Garg, Nisha. / ROS Signalling of inflammatory cytokines during trypanosoma cruzi infection. In: Advances in Parasitology. 2011 ; Vol. 76. pp. 153-170.
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