Runner's dystonia

Laura Wu, Joseph Jankovic

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Adult-onset focal dystonia in the upper limbs is well characterized whereas such dystonia has been rarely reported in the lower limbs, especially in proximal parts. When such focal dystonia occurs in an athlete it is often wrongly attributed to an orthopedic disorder. We present five cases, three female and two male with mean age of 44.6 ± 10.43 years, mean age at onset of 37.4 ± 10.33 years, and mean duration of symptoms for 7.2 ± 4.44 years, who initially noted dystonia of one leg during long-distance running. The clinical features of dystonia in these long-distance runners overlap with those of more recognizable forms of focal dystonia including relief with sensory or motor "tricks". They also share features with paroxysmal dyskinesia and carbamazepine markedly ameliorated the symptoms at least in one patient. One patient benefited from an oral anticholinergic, one from levodopa, and another two patients benefited from repeat botulinum toxin injections. Our patients differed from the typical childhood-onset leg dystonia, such as the DYT1 dystonia, in that there was no family history of dystonia and the leg dystonia remained focal without spreading to other body parts. Two of our patients had prior injury to the affected leg within 1 year prior to the onset of the dystonia, raising the possibility of peripherally-induced dystonia. We draw attention to this rare, disabling, adult-onset focal dystonia involving proximal lower limbs. When recognized early, it may be treated effectively with either anticholinergic drugs, anticonvulsants, levodopa, or botulinum toxin injections.

Original languageEnglish (US)
Pages (from-to)73-76
Number of pages4
JournalJournal of the Neurological Sciences
Volume251
Issue number1-2
DOIs
StatePublished - Dec 21 2006
Externally publishedYes

Fingerprint

Dystonic Disorders
Dystonia
Leg
Botulinum Toxins
Cholinergic Antagonists
Levodopa
Lower Extremity
Musculoskeletal Diseases
Chorea
Injections
Carbamazepine
Human Body
Age of Onset
Upper Extremity
Athletes
Anticonvulsants
Wounds and Injuries

Keywords

  • Botulinum toxin
  • Dystonia
  • Injury
  • Paroxysmal
  • Running

ASJC Scopus subject areas

  • Aging
  • Clinical Neurology
  • Surgery
  • Developmental Neuroscience
  • Neurology
  • Neuroscience(all)

Cite this

Runner's dystonia. / Wu, Laura; Jankovic, Joseph.

In: Journal of the Neurological Sciences, Vol. 251, No. 1-2, 21.12.2006, p. 73-76.

Research output: Contribution to journalArticle

Wu, Laura ; Jankovic, Joseph. / Runner's dystonia. In: Journal of the Neurological Sciences. 2006 ; Vol. 251, No. 1-2. pp. 73-76.
@article{ebb344cbf3144aa4ab3d00632b28ee34,
title = "Runner's dystonia",
abstract = "Adult-onset focal dystonia in the upper limbs is well characterized whereas such dystonia has been rarely reported in the lower limbs, especially in proximal parts. When such focal dystonia occurs in an athlete it is often wrongly attributed to an orthopedic disorder. We present five cases, three female and two male with mean age of 44.6 ± 10.43 years, mean age at onset of 37.4 ± 10.33 years, and mean duration of symptoms for 7.2 ± 4.44 years, who initially noted dystonia of one leg during long-distance running. The clinical features of dystonia in these long-distance runners overlap with those of more recognizable forms of focal dystonia including relief with sensory or motor {"}tricks{"}. They also share features with paroxysmal dyskinesia and carbamazepine markedly ameliorated the symptoms at least in one patient. One patient benefited from an oral anticholinergic, one from levodopa, and another two patients benefited from repeat botulinum toxin injections. Our patients differed from the typical childhood-onset leg dystonia, such as the DYT1 dystonia, in that there was no family history of dystonia and the leg dystonia remained focal without spreading to other body parts. Two of our patients had prior injury to the affected leg within 1 year prior to the onset of the dystonia, raising the possibility of peripherally-induced dystonia. We draw attention to this rare, disabling, adult-onset focal dystonia involving proximal lower limbs. When recognized early, it may be treated effectively with either anticholinergic drugs, anticonvulsants, levodopa, or botulinum toxin injections.",
keywords = "Botulinum toxin, Dystonia, Injury, Paroxysmal, Running",
author = "Laura Wu and Joseph Jankovic",
year = "2006",
month = "12",
day = "21",
doi = "10.1016/j.jns.2006.09.003",
language = "English (US)",
volume = "251",
pages = "73--76",
journal = "Journal of the Neurological Sciences",
issn = "0022-510X",
publisher = "Elsevier",
number = "1-2",

}

TY - JOUR

T1 - Runner's dystonia

AU - Wu, Laura

AU - Jankovic, Joseph

PY - 2006/12/21

Y1 - 2006/12/21

N2 - Adult-onset focal dystonia in the upper limbs is well characterized whereas such dystonia has been rarely reported in the lower limbs, especially in proximal parts. When such focal dystonia occurs in an athlete it is often wrongly attributed to an orthopedic disorder. We present five cases, three female and two male with mean age of 44.6 ± 10.43 years, mean age at onset of 37.4 ± 10.33 years, and mean duration of symptoms for 7.2 ± 4.44 years, who initially noted dystonia of one leg during long-distance running. The clinical features of dystonia in these long-distance runners overlap with those of more recognizable forms of focal dystonia including relief with sensory or motor "tricks". They also share features with paroxysmal dyskinesia and carbamazepine markedly ameliorated the symptoms at least in one patient. One patient benefited from an oral anticholinergic, one from levodopa, and another two patients benefited from repeat botulinum toxin injections. Our patients differed from the typical childhood-onset leg dystonia, such as the DYT1 dystonia, in that there was no family history of dystonia and the leg dystonia remained focal without spreading to other body parts. Two of our patients had prior injury to the affected leg within 1 year prior to the onset of the dystonia, raising the possibility of peripherally-induced dystonia. We draw attention to this rare, disabling, adult-onset focal dystonia involving proximal lower limbs. When recognized early, it may be treated effectively with either anticholinergic drugs, anticonvulsants, levodopa, or botulinum toxin injections.

AB - Adult-onset focal dystonia in the upper limbs is well characterized whereas such dystonia has been rarely reported in the lower limbs, especially in proximal parts. When such focal dystonia occurs in an athlete it is often wrongly attributed to an orthopedic disorder. We present five cases, three female and two male with mean age of 44.6 ± 10.43 years, mean age at onset of 37.4 ± 10.33 years, and mean duration of symptoms for 7.2 ± 4.44 years, who initially noted dystonia of one leg during long-distance running. The clinical features of dystonia in these long-distance runners overlap with those of more recognizable forms of focal dystonia including relief with sensory or motor "tricks". They also share features with paroxysmal dyskinesia and carbamazepine markedly ameliorated the symptoms at least in one patient. One patient benefited from an oral anticholinergic, one from levodopa, and another two patients benefited from repeat botulinum toxin injections. Our patients differed from the typical childhood-onset leg dystonia, such as the DYT1 dystonia, in that there was no family history of dystonia and the leg dystonia remained focal without spreading to other body parts. Two of our patients had prior injury to the affected leg within 1 year prior to the onset of the dystonia, raising the possibility of peripherally-induced dystonia. We draw attention to this rare, disabling, adult-onset focal dystonia involving proximal lower limbs. When recognized early, it may be treated effectively with either anticholinergic drugs, anticonvulsants, levodopa, or botulinum toxin injections.

KW - Botulinum toxin

KW - Dystonia

KW - Injury

KW - Paroxysmal

KW - Running

UR - http://www.scopus.com/inward/record.url?scp=33751255037&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33751255037&partnerID=8YFLogxK

U2 - 10.1016/j.jns.2006.09.003

DO - 10.1016/j.jns.2006.09.003

M3 - Article

C2 - 17097111

AN - SCOPUS:33751255037

VL - 251

SP - 73

EP - 76

JO - Journal of the Neurological Sciences

JF - Journal of the Neurological Sciences

SN - 0022-510X

IS - 1-2

ER -