TY - JOUR
T1 - Safety and Effectiveness of Neuro-thrombectomy on Single compared to Biplane Angiography Systems
AU - The RADON Investigators
AU - Guenego, Adrien
AU - Mosimann, Pascal J.
AU - Wintermark, Max
AU - Heit, Jeremy J.
AU - Zuber, Kevin
AU - Dobrocky, Tomas
AU - Lotterie, Jean Albert
AU - Nicholson, Patrick
AU - Marcellus, David G.
AU - Olivot, Jean Marc
AU - Gonzalez, Nestor
AU - Blanc, Raphaël
AU - Pereira, Vitor Mendes
AU - Gralla, Jan
AU - Kaesmacher, Johannes
AU - Fahed, Robert
AU - Piotin, Michel
AU - Cognard, Christophe
AU - Piechowiak, Eike
AU - Mordasini, Pasquale
AU - Zibold, Felix
AU - Ducroux, Celina
AU - Bonneville, Fabrice
AU - Darcourt, Jean
AU - Vukasinovic, Ivan
AU - Januel, Anne Christine
AU - Monfraix, Sylvie
AU - Michelozzi, Caterina
AU - Tall, Philippe
AU - Mazighi, Mikael
AU - Desilles, Jean Philippe
AU - Ciccio, Gabriele
AU - Smajda, Stanislas
AU - Redjem, Hocine
AU - Maier, Benjamin
AU - Martin, Blake W.
AU - Guenego, Elisa
AU - Carbillet, Fanny
N1 - Publisher Copyright:
© 2020, The Author(s).
PY - 2020/12/1
Y1 - 2020/12/1
N2 - An increasing number of centers not necessarily equipped with biplane (BP) angiosuites are performing mechanical thrombectomy (MT) in acute ischemic stroke patients. We assessed whether MT performed on single-plane (SP) is equivalent in terms of safety, effectiveness, radiation and contrast agent exposure. Consecutive patients treated by MT in four high volume centers between January 2014 and May 2017 were included. Demographic and MT characteristics were assessed and compared between SP and BP. Of 906 patients treated by MT, 576 (64%) were handled on a BP system. After multivariate analysis, contrast load and fluoroscopy duration were significantly lower in the BP group [100vs200mL, relative effect 0.85 (CI: 0.79–0.92), p = 0.0002; 22 vs 27 min, relative effect 0.84 (CI: 0.76–0.93), p = 0.0008, respectively]. There was no difference in recanalization (modified Thrombolysis-In-Cerebral-Infarction 2b-3), good clinical outcome (modified Rankin Scale 0–2), complications rates, procedure duration or radiation exposure. A three-vessel diagnostic angiogram performed prior to MT led to a significant increase in procedure duration (15% increase, p = 0.05), radiation exposure (33% increase, p < 0.0001) and contrast load (125% increase, p < 0.0001). Mechanical neuro-thrombectomy seems equally safe and effective on a single or biplane angiography system despite increased contrast load and fluoroscopy duration on the former.
AB - An increasing number of centers not necessarily equipped with biplane (BP) angiosuites are performing mechanical thrombectomy (MT) in acute ischemic stroke patients. We assessed whether MT performed on single-plane (SP) is equivalent in terms of safety, effectiveness, radiation and contrast agent exposure. Consecutive patients treated by MT in four high volume centers between January 2014 and May 2017 were included. Demographic and MT characteristics were assessed and compared between SP and BP. Of 906 patients treated by MT, 576 (64%) were handled on a BP system. After multivariate analysis, contrast load and fluoroscopy duration were significantly lower in the BP group [100vs200mL, relative effect 0.85 (CI: 0.79–0.92), p = 0.0002; 22 vs 27 min, relative effect 0.84 (CI: 0.76–0.93), p = 0.0008, respectively]. There was no difference in recanalization (modified Thrombolysis-In-Cerebral-Infarction 2b-3), good clinical outcome (modified Rankin Scale 0–2), complications rates, procedure duration or radiation exposure. A three-vessel diagnostic angiogram performed prior to MT led to a significant increase in procedure duration (15% increase, p = 0.05), radiation exposure (33% increase, p < 0.0001) and contrast load (125% increase, p < 0.0001). Mechanical neuro-thrombectomy seems equally safe and effective on a single or biplane angiography system despite increased contrast load and fluoroscopy duration on the former.
UR - https://www.scopus.com/pages/publications/85081668992
UR - https://www.scopus.com/pages/publications/85081668992#tab=citedBy
U2 - 10.1038/s41598-020-60851-4
DO - 10.1038/s41598-020-60851-4
M3 - Article
C2 - 32161286
AN - SCOPUS:85081668992
SN - 2045-2322
VL - 10
JO - Scientific reports
JF - Scientific reports
IS - 1
M1 - 4470
ER -