Safety and efficacy of the surpass streamline for intracranial aneurysms (SESSIA): A multi-center US experience pooled analysis

Juan Vivanco-Suarez, Alan Mendez-Ruiz, Mudassir Farooqui, Kimon Bekelis, Justin A. Singer, Kainaat Javed, David J. Altschul, Johanna T. Fifi, Stavros Matsoukas, Jared Cooper, Fawaz Al-Mufti, Bradley Gross, Brian Jankowitz, Peter T. Kan, Muhammad Hafeez, Emanuele Orru, Andres Dajles, Milagros Galecio-Castillo, Cynthia B. Zevallos, Ajay K. WakhlooSantiago Ortega-Gutierrez

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Background and purpose: Flow diversion has established as standard treatment for intracranial aneurysms, the Surpass Streamline is the only FDA-approved braided cobalt/chromium alloy implant with 72-96 wires. We aimed to determine the safety and efficacy of the Surpass in a post-marketing large United States cohort. Materials and methods: This is a retrospective multicenter study of consecutive patients treated with the Surpass for intracranial aneurysms between 2018 and 2021. Baseline demographics, comorbidities, and aneurysm characteristics were collected. Efficacy endpoint included aneurysm occlusion on radiographic follow-up. Safety endpoints were major ipsilateral ischemic stroke or treatment-related death. Results: A total of 277 patients with 314 aneurysms were included. Median age was 60 years, 202 (73%) patients were females. Hypertension was the most common comorbidity in 156 (56%) patients. The most common location of the aneurysms was the anterior circulation in 89% (279/314). Mean aneurysm dome width was 5.77 ± 4.75 mm, neck width was 4.22 ± 3.83 mm, and dome/neck ratio was 1.63 ± 1.26. Small-sized aneurysms were 185 (59%). Single device was used in 94% of the patients, mean number of devices per patient was 1.06. At final follow-up, complete obliteration rate was 81% (194/239). Major stroke and death were encountered in 7 (3%) and 6 (2%) cases, respectively. Conclusion: This is the largest cohort study using a 72–96 wire flow diverter. The Surpass Streamline demonstrated a favorable safety and efficacy profile, making it a valuable option for treating not only large but also wide-necked small and medium-sized intracranial aneurysms.

Original languageEnglish (US)
Pages (from-to)589-598
Number of pages10
JournalInterventional Neuroradiology
Issue number5
StatePublished - Oct 2023


  • Intracranial aneurysm
  • flow diverter
  • interventional
  • subarachnoid hemorrhage

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine


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