Salmonella Phage S16 Tail Fiber Adhesin Features a Rare Polyglycine Rich Domain for Host Recognition

Matthew Dunne; Jenna M. Denyes; Helena Arndt; Martin J. Loessner; Petr G. Leiman; Jochen Klumpp

doi:10.1016/j.str.2018.07.017

Salmonella Phage S16 Tail Fiber Adhesin Features a Rare Polyglycine Rich Domain for Host Recognition

Matthew Dunne
, Jenna M. Denyes
, Helena Arndt
, Martin J. Loessner
, Petr G. Leiman
, Jochen Klumpp

Biochemistry & Molecular Biology

Research output: Contribution to journal › Article › peer-review

87 Scopus citations

Abstract

Dunne et al. present the crystal structure of the adhesin tip (gp38) of the Salmonella bacteriophage S16 long tail fiber. Gp38 contains rare polyglycine type II (PG _II ) helices arranged as a three-layered “PG _II sandwich.” Surface residues on the PG _II sandwich are key determinants of phage-host interaction.

Original language	English (US)
Pages (from-to)	1573-1582.e4
Journal	Structure
Volume	26
Issue number	12
DOIs	https://doi.org/10.1016/j.str.2018.07.017
State	Published - Dec 4 2018

Keywords

Salmonella
X-ray crystallography
bacteriophage
polyglycine sandwich
polyglycine type II helix

ASJC Scopus subject areas

Structural Biology
Molecular Biology

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10.1016/j.str.2018.07.017

Cite this

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title = "Salmonella Phage S16 Tail Fiber Adhesin Features a Rare Polyglycine Rich Domain for Host Recognition",

abstract = " Dunne et al. present the crystal structure of the adhesin tip (gp38) of the Salmonella bacteriophage S16 long tail fiber. Gp38 contains rare polyglycine type II (PG II ) helices arranged as a three-layered {\textquotedblleft}PG II sandwich.{\textquotedblright} Surface residues on the PG II sandwich are key determinants of phage-host interaction.",

keywords = "Salmonella, X-ray crystallography, bacteriophage, polyglycine sandwich, polyglycine type II helix",

author = "Matthew Dunne and Denyes, \{Jenna M.\} and Helena Arndt and Loessner, \{Martin J.\} and Leiman, \{Petr G.\} and Jochen Klumpp",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Ltd",

year = "2018",

month = dec,

day = "4",

doi = "10.1016/j.str.2018.07.017",

language = "English (US)",

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T1 - Salmonella Phage S16 Tail Fiber Adhesin Features a Rare Polyglycine Rich Domain for Host Recognition

AU - Dunne, Matthew

AU - Denyes, Jenna M.

AU - Arndt, Helena

AU - Loessner, Martin J.

AU - Leiman, Petr G.

AU - Klumpp, Jochen

PY - 2018/12/4

Y1 - 2018/12/4

N2 - Dunne et al. present the crystal structure of the adhesin tip (gp38) of the Salmonella bacteriophage S16 long tail fiber. Gp38 contains rare polyglycine type II (PG II ) helices arranged as a three-layered “PG II sandwich.” Surface residues on the PG II sandwich are key determinants of phage-host interaction.

AB - Dunne et al. present the crystal structure of the adhesin tip (gp38) of the Salmonella bacteriophage S16 long tail fiber. Gp38 contains rare polyglycine type II (PG II ) helices arranged as a three-layered “PG II sandwich.” Surface residues on the PG II sandwich are key determinants of phage-host interaction.

KW - Salmonella

KW - X-ray crystallography

KW - bacteriophage

KW - polyglycine sandwich

KW - polyglycine type II helix

UR - https://www.scopus.com/pages/publications/85057913408

UR - https://www.scopus.com/pages/publications/85057913408#tab=citedBy

U2 - 10.1016/j.str.2018.07.017

DO - 10.1016/j.str.2018.07.017

M3 - Article

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AN - SCOPUS:85057913408

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JO - Structure

JF - Structure

IS - 12

ER -

Salmonella Phage S16 Tail Fiber Adhesin Features a Rare Polyglycine Rich Domain for Host Recognition

Abstract

Keywords

ASJC Scopus subject areas

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