SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species

Mehdi Moustaqil, Emma Ollivier, Hsin Ping Chiu, Sarah Van Tol, Paulina Rudolffi-Soto, Christian Stevens, Akshay Bhumkar, Dominic J.B. Hunter, Alexander N. Freiberg, David Jacques, Benhur Lee, Emma Sierecki, Yann Gambin

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Medicine and Dentistry

Biochemistry, Genetics and Molecular Biology

Immunology and Microbiology