Keyphrases
Small Molecule Inhibitors
100%
Membrane Permeable
100%
High-fat Diet-induced Obesity
100%
Nicotinamide N-methyltransferase
100%
Methyltransferase Inhibitor
64%
Nicotinamide Adenine Dinucleotide (NAD+)
28%
Obesity
21%
Methionine
21%
Small Molecules
14%
Cellular Energy
14%
Methyltransferase
14%
Membrane Permeability
14%
Salvage Pathway
14%
Lipogenesis
14%
Diet-induced Obese Mice
14%
Adverse Effects
7%
Mechanism of Action
7%
Type 2 Diabetes Mellitus (T2DM)
7%
Intracellular Level
7%
Cholesterol
7%
Food Intake
7%
High-fat Diet
7%
Drug Target
7%
Cellular Metabolism
7%
Energy Homeostasis
7%
Plasma Lipids
7%
Adipocyte
7%
Metabolic Homeostasis
7%
Reaction Products
7%
Anti-obesity
7%
Reduced Body
7%
White Adipose Tissue
7%
Diet-induced Obesity
7%
Total Cholesterol Level
7%
High Selectivity
7%
Active Transport
7%
High Permeability
7%
Artificial Membrane
7%
Primary Amines
7%
Therapeutic Mechanism
7%
Permeability Properties
7%
Adipocyte Size
7%
Cytoplasmic Enzyme
7%
Passive Transport
7%
Adipose Mass
7%
Metabolic Conditions
7%
Mechanistic Properties
7%
Physiological Properties
7%
Cultured Adipocytes
7%
Energy Regulator
7%
Permeability-selectivity Trade-off
7%
Obesity Indices
7%
Caco-2 Cell Viability
7%
New Mechanisms of Action
7%
Metabolic Comorbidities
7%
Medicine and Dentistry
Nicotinamide
100%
Diet Induced Obesity
100%
Methyltransferase
100%
Methyltransferase Inhibitor
64%
Nicotinamide Adenine Dinucleotide
28%
Adipocyte
21%
Methionine
21%
Cell Energy
14%
Membrane Permeability
14%
Lipogenesis
14%
Adverse Event
7%
Metabolite
7%
Homeostasis
7%
Maturity Onset Diabetes of the Young
7%
Food Intake
7%
Adipose Tissue
7%
Body Weight
7%
Cell Metabolism
7%
Caco-2
7%
Burden of Obesity
7%
Active Transport
7%
Passive Transport
7%
Comorbidity
7%
High Fat Food
7%
Antiobesity Drugs
7%
Biochemistry, Genetics and Molecular Biology
Small Molecule
100%
Nicotinamide N-Methyltransferase
100%
Nicotinamide Adenine Dinucleotide
28%
Enzyme
21%
Methyltransferase
21%
Adipocyte
21%
Methionine
21%
Cell Energy
14%
Mouse Mutant
14%
Membrane Permeability
14%
Lipogenesis
14%
Metabolite
7%
Homeostasis
7%
Cell Metabolism
7%
Body Weight
7%
Cell Assay
7%
Drug Mechanism
7%
Blood Lipids
7%
Artificial Membrane
7%
Total Cholesterol Level
7%
Comorbidity
7%
Blood Plasma
7%
Pharmacology, Toxicology and Pharmaceutical Science
Methyltransferase
100%
Nicotinamide
100%
Diet Induced Obesity
100%
Methyltransferase Inhibitor
64%
Nicotinamide Adenine Dinucleotide
28%
Methionine
21%
Adverse Event
7%
Drug Action
7%
Comorbidity
7%
Non Insulin Dependent Diabetes Mellitus
7%
Antiobesity Drugs
7%