Senescence of primary amniotic cells via oxidative DNA damage

Agriculture & Biology

• cigarettes 88%
• DNA damage 86%
• smoke 82%
• amnion 82%
• reactive oxygen species 72%
• premature birth 61%
• mitogen-activated protein kinase 47%
• extracts 38%
• acetylcysteine 38%
• comet assay 34%
• water 30%
• cells 27%
• pregnancy complications 25%
• cell senescence 21%
• extraembryonic membranes 20%
• antioxidants 19%
• nucleobases 18%
• fluorescein 16%
• assays 15%
• post-translational modification 15%
• etiology 15%
• apoptosis 13%
• enzymes 13%
• phosphorylation 12%
• epithelial cells 12%
• phosphotransferases (kinases) 12%
• Western blotting 12%
• cell culture 11%
• oxidative stress 11%
• culture media 10%
• DNA 7%
• methodology 3%

Medicine & Life Sciences

• DNA Damage 76%
• Amnion 71%
• Reactive Oxygen Species 70%
• Smoke 70%
• Tobacco Products 69%
• Water 48%
• Premature Birth 46%
• p38 Mitogen-Activated Protein Kinases 45%
• Rupture 37%
• Comet Assay 35%
• Enzyme Assays 33%
• Acetylcysteine 33%
• Cellular Senescence 32%
• Membranes 26%
• Antioxidants 21%
• Extraembryonic Membranes 19%
• Pregnancy Complications 16%
• DNA 16%
• Fluorescein 15%
• Post Translational Protein Processing 15%
• Culture Media 13%
• Phosphotransferases 11%
• Cell Culture Techniques 11%
• Oxidative Stress 10%
• Epithelial Cells 10%
• Phosphorylation 10%
• Western Blotting 9%
• Apoptosis 8%

Chemical Compounds

• Smoke 100%
• Reactive Oxygen Metabolite 82%
• Water Soluble 67%
• N-Acetyl-L-Cysteine 52%
• Comet Assay 47%
• Antioxidant Agent 26%
• Length 20%
• Culture Media 18%
• Oxidative Stress 17%
• Modification 9%
• Dioxygen 8%