Sensitivity and Specificity of an HIV Antibody Assay

R. A. Chase; H. A. Kessler; A. L. Landay; A. Vahey; B. Blaauw; D. Chudwin; G. Dawson; J. Heller; L. Falk

doi:10.1089/aid.1.1986.2.369

Sensitivity and Specificity of an HIV Antibody Assay

R. A. Chase, H. A. Kessler, A. L. Landay, A. Vahey, B. Blaauw, D. Chudwin, G. Dawson, J. Heller, L. Falk

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

We have evaluated a new enzyme immunoassay (EIA) to measure IgG antibodies (Abs) to HIV in patients with AIDS, AIDS-related complex (ARC), AIDS contacts (AC), and low risk controls. Twenty-nine (94%) of 31 AIDS, 27 (96%) of 26 ARC, 12 (54%) of 22 AC, and 1 (2%) of 60 control patients were anti-HIV Ab positive by this assay. Positive results were confirmed by Western blot analysis. The EIA for anti-HIV evaluated in this study is sensitive and specific in identifying individuals who have been infected by this retrovirus.

Original language	English (US)
Pages (from-to)	369-375
Number of pages	7
Journal	AIDS Research
Volume	2
Issue number	4
DOIs	https://doi.org/10.1089/aid.1.1986.2.369
State	Published - 1986
Externally published	Yes

ASJC Scopus subject areas

Immunology
Virology

Access to Document

10.1089/aid.1.1986.2.369

Cite this

@article{92e52b5b2e0f49b1a953719ba5c6435c,

title = "Sensitivity and Specificity of an HIV Antibody Assay",

abstract = "We have evaluated a new enzyme immunoassay (EIA) to measure IgG antibodies (Abs) to HIV in patients with AIDS, AIDS-related complex (ARC), AIDS contacts (AC), and low risk controls. Twenty-nine (94%) of 31 AIDS, 27 (96%) of 26 ARC, 12 (54%) of 22 AC, and 1 (2%) of 60 control patients were anti-HIV Ab positive by this assay. Positive results were confirmed by Western blot analysis. The EIA for anti-HIV evaluated in this study is sensitive and specific in identifying individuals who have been infected by this retrovirus.",

author = "Chase, {R. A.} and Kessler, {H. A.} and Landay, {A. L.} and A. Vahey and B. Blaauw and D. Chudwin and G. Dawson and J. Heller and L. Falk",

year = "1986",

doi = "10.1089/aid.1.1986.2.369",

language = "English (US)",

volume = "2",

pages = "369--375",

journal = "AIDS Research",

issn = "0737-6006",

publisher = "Mary Ann Liebert Inc.",

number = "4",

}

TY - JOUR

T1 - Sensitivity and Specificity of an HIV Antibody Assay

AU - Chase, R. A.

AU - Kessler, H. A.

AU - Landay, A. L.

AU - Vahey, A.

AU - Blaauw, B.

AU - Chudwin, D.

AU - Dawson, G.

AU - Heller, J.

AU - Falk, L.

PY - 1986

Y1 - 1986

N2 - We have evaluated a new enzyme immunoassay (EIA) to measure IgG antibodies (Abs) to HIV in patients with AIDS, AIDS-related complex (ARC), AIDS contacts (AC), and low risk controls. Twenty-nine (94%) of 31 AIDS, 27 (96%) of 26 ARC, 12 (54%) of 22 AC, and 1 (2%) of 60 control patients were anti-HIV Ab positive by this assay. Positive results were confirmed by Western blot analysis. The EIA for anti-HIV evaluated in this study is sensitive and specific in identifying individuals who have been infected by this retrovirus.

AB - We have evaluated a new enzyme immunoassay (EIA) to measure IgG antibodies (Abs) to HIV in patients with AIDS, AIDS-related complex (ARC), AIDS contacts (AC), and low risk controls. Twenty-nine (94%) of 31 AIDS, 27 (96%) of 26 ARC, 12 (54%) of 22 AC, and 1 (2%) of 60 control patients were anti-HIV Ab positive by this assay. Positive results were confirmed by Western blot analysis. The EIA for anti-HIV evaluated in this study is sensitive and specific in identifying individuals who have been infected by this retrovirus.

UR - http://www.scopus.com/inward/record.url?scp=0022885166&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022885166&partnerID=8YFLogxK

U2 - 10.1089/aid.1.1986.2.369

DO - 10.1089/aid.1.1986.2.369

M3 - Article

C2 - 3545238

AN - SCOPUS:0022885166

SN - 0737-6006

VL - 2

SP - 369

EP - 375

JO - AIDS Research

JF - AIDS Research

IS - 4

ER -

Sensitivity and Specificity of an HIV Antibody Assay

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this