Sensitivity and Specificity of an HIV Antibody Assay

R. A. Chase, H. A. Kessler, A. L. Landay, A. Vahey, B. Blaauw, D. Chudwin, G. Dawson, J. Heller, L. Falk

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


We have evaluated a new enzyme immunoassay (EIA) to measure IgG antibodies (Abs) to HIV in patients with AIDS, AIDS-related complex (ARC), AIDS contacts (AC), and low risk controls. Twenty-nine (94%) of 31 AIDS, 27 (96%) of 26 ARC, 12 (54%) of 22 AC, and 1 (2%) of 60 control patients were anti-HIV Ab positive by this assay. Positive results were confirmed by Western blot analysis. The EIA for anti-HIV evaluated in this study is sensitive and specific in identifying individuals who have been infected by this retrovirus.

Original languageEnglish (US)
Pages (from-to)369-375
Number of pages7
JournalAIDS Research
Issue number4
StatePublished - 1986
Externally publishedYes

ASJC Scopus subject areas

  • Immunology
  • Virology


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