Sensitivity and Specificity of an HIV Antibody Assay

R. A. Chase; H. A. Kessler; A. L. Landay; A. Vahey; B. Blaauw; D. Chudwin; G. Dawson; J. Heller; L. Falk

doi:10.1089/aid.1.1986.2.369

Sensitivity and Specificity of an HIV Antibody Assay

R. A. Chase
, H. A. Kessler
, A. L. Landay
, A. Vahey
, B. Blaauw
, D. Chudwin
, G. Dawson
, J. Heller
, L. Falk

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

We have evaluated a new enzyme immunoassay (EIA) to measure IgG antibodies (Abs) to HIV in patients with AIDS, AIDS-related complex (ARC), AIDS contacts (AC), and low risk controls. Twenty-nine (94%) of 31 AIDS, 27 (96%) of 26 ARC, 12 (54%) of 22 AC, and 1 (2%) of 60 control patients were anti-HIV Ab positive by this assay. Positive results were confirmed by Western blot analysis. The EIA for anti-HIV evaluated in this study is sensitive and specific in identifying individuals who have been infected by this retrovirus.

Original language	English (US)
Pages (from-to)	369-375
Number of pages	7
Journal	AIDS Research
Volume	2
Issue number	4
DOIs	https://doi.org/10.1089/aid.1.1986.2.369
State	Published - 1986
Externally published	Yes

ASJC Scopus subject areas

Immunology
Virology

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10.1089/aid.1.1986.2.369

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title = "Sensitivity and Specificity of an HIV Antibody Assay",

abstract = "We have evaluated a new enzyme immunoassay (EIA) to measure IgG antibodies (Abs) to HIV in patients with AIDS, AIDS-related complex (ARC), AIDS contacts (AC), and low risk controls. Twenty-nine (94\%) of 31 AIDS, 27 (96\%) of 26 ARC, 12 (54\%) of 22 AC, and 1 (2\%) of 60 control patients were anti-HIV Ab positive by this assay. Positive results were confirmed by Western blot analysis. The EIA for anti-HIV evaluated in this study is sensitive and specific in identifying individuals who have been infected by this retrovirus.",

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doi = "10.1089/aid.1.1986.2.369",

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T1 - Sensitivity and Specificity of an HIV Antibody Assay

AU - Chase, R. A.

AU - Kessler, H. A.

AU - Landay, A. L.

AU - Vahey, A.

AU - Blaauw, B.

AU - Chudwin, D.

AU - Dawson, G.

AU - Heller, J.

AU - Falk, L.

PY - 1986

Y1 - 1986

N2 - We have evaluated a new enzyme immunoassay (EIA) to measure IgG antibodies (Abs) to HIV in patients with AIDS, AIDS-related complex (ARC), AIDS contacts (AC), and low risk controls. Twenty-nine (94%) of 31 AIDS, 27 (96%) of 26 ARC, 12 (54%) of 22 AC, and 1 (2%) of 60 control patients were anti-HIV Ab positive by this assay. Positive results were confirmed by Western blot analysis. The EIA for anti-HIV evaluated in this study is sensitive and specific in identifying individuals who have been infected by this retrovirus.

AB - We have evaluated a new enzyme immunoassay (EIA) to measure IgG antibodies (Abs) to HIV in patients with AIDS, AIDS-related complex (ARC), AIDS contacts (AC), and low risk controls. Twenty-nine (94%) of 31 AIDS, 27 (96%) of 26 ARC, 12 (54%) of 22 AC, and 1 (2%) of 60 control patients were anti-HIV Ab positive by this assay. Positive results were confirmed by Western blot analysis. The EIA for anti-HIV evaluated in this study is sensitive and specific in identifying individuals who have been infected by this retrovirus.

UR - https://www.scopus.com/pages/publications/0022885166

UR - https://www.scopus.com/pages/publications/0022885166#tab=citedBy

U2 - 10.1089/aid.1.1986.2.369

DO - 10.1089/aid.1.1986.2.369

M3 - Article

C2 - 3545238

AN - SCOPUS:0022885166

SN - 0737-6006

VL - 2

SP - 369

EP - 375

JO - AIDS Research

JF - AIDS Research

IS - 4

ER -

Sensitivity and Specificity of an HIV Antibody Assay

Abstract

ASJC Scopus subject areas

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