Separation of chiral phosphorus compounds on the substituted β-cyclodextrin stationary phase in normal-phase liquid chromatography

H. Chen, X. Y. Lu, R. Y. Gao, J. Zhou, Q. S. Wang

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

The separation of enantiomers of a series of eighteen novel nitrogen mustard linked phosphoryl diamide derivatives was investigated on the prepared phenyl carbamate derivative β-cyclodextrin bonded phase in normal-phase HPLC. Some of the enantiomers could be separated in baseline. The chiral recognition mechanism was also suggested for the separation of chiral phosphorus organic compound.

Original languageEnglish (US)
Pages (from-to)533-536
Number of pages4
JournalChinese Journal of Chemistry
Volume18
Issue number4
StatePublished - Jan 1 2000
Externally publishedYes

Keywords

  • Chiral stationary phase
  • Nitrogen mustard linked phosphoryl diamide derivatives
  • Normal-phase LC
  • β-cyclodextrin

ASJC Scopus subject areas

  • Chemistry(all)

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