Separation of chiral phosphorus compounds on the substituted β-cyclodextrin stationary phase in normal-phase liquid chromatography

H. Chen; X. Y. Lu; R. Y. Gao; J. Zhou; Q. S. Wang

doi:10.1002/cjoc.20000180414

Separation of chiral phosphorus compounds on the substituted β-cyclodextrin stationary phase in normal-phase liquid chromatography

H. Chen, X. Y. Lu, R. Y. Gao, J. Zhou, Q. S. Wang

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

The separation of enantiomers of a series of eighteen novel nitrogen mustard linked phosphoryl diamide derivatives was investigated on the prepared phenyl carbamate derivative β-cyclodextrin bonded phase in normal-phase HPLC. Some of the enantiomers could be separated in baseline. The chiral recognition mechanism was also suggested for the separation of chiral phosphorus organic compound.

Original language	English (US)
Pages (from-to)	533-536
Number of pages	4
Journal	Chinese Journal of Chemistry
Volume	18
Issue number	4
DOIs	https://doi.org/10.1002/cjoc.20000180414
State	Published - 2000
Externally published	Yes

Keywords

Chiral stationary phase
Nitrogen mustard linked phosphoryl diamide derivatives
Normal-phase LC
β-cyclodextrin

ASJC Scopus subject areas

General Chemistry

Access to Document

10.1002/cjoc.20000180414

Cite this

@article{bec911c7124d404183ed0d079bde3e68,

title = "Separation of chiral phosphorus compounds on the substituted β-cyclodextrin stationary phase in normal-phase liquid chromatography",

abstract = "The separation of enantiomers of a series of eighteen novel nitrogen mustard linked phosphoryl diamide derivatives was investigated on the prepared phenyl carbamate derivative β-cyclodextrin bonded phase in normal-phase HPLC. Some of the enantiomers could be separated in baseline. The chiral recognition mechanism was also suggested for the separation of chiral phosphorus organic compound.",

keywords = "Chiral stationary phase, Nitrogen mustard linked phosphoryl diamide derivatives, Normal-phase LC, β-cyclodextrin",

author = "H. Chen and Lu, {X. Y.} and Gao, {R. Y.} and J. Zhou and Wang, {Q. S.}",

year = "2000",

doi = "10.1002/cjoc.20000180414",

language = "English (US)",

volume = "18",

pages = "533--536",

journal = "Chinese Journal of Chemistry",

issn = "1001-604X",

publisher = "Shanghai Institute of Organic Chemistry",

number = "4",

}

TY - JOUR

T1 - Separation of chiral phosphorus compounds on the substituted β-cyclodextrin stationary phase in normal-phase liquid chromatography

AU - Chen, H.

AU - Lu, X. Y.

AU - Gao, R. Y.

AU - Zhou, J.

AU - Wang, Q. S.

PY - 2000

Y1 - 2000

N2 - The separation of enantiomers of a series of eighteen novel nitrogen mustard linked phosphoryl diamide derivatives was investigated on the prepared phenyl carbamate derivative β-cyclodextrin bonded phase in normal-phase HPLC. Some of the enantiomers could be separated in baseline. The chiral recognition mechanism was also suggested for the separation of chiral phosphorus organic compound.

AB - The separation of enantiomers of a series of eighteen novel nitrogen mustard linked phosphoryl diamide derivatives was investigated on the prepared phenyl carbamate derivative β-cyclodextrin bonded phase in normal-phase HPLC. Some of the enantiomers could be separated in baseline. The chiral recognition mechanism was also suggested for the separation of chiral phosphorus organic compound.

KW - Chiral stationary phase

KW - Nitrogen mustard linked phosphoryl diamide derivatives

KW - Normal-phase LC

KW - β-cyclodextrin

UR - http://www.scopus.com/inward/record.url?scp=0033829032&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033829032&partnerID=8YFLogxK

U2 - 10.1002/cjoc.20000180414

DO - 10.1002/cjoc.20000180414

M3 - Article

AN - SCOPUS:0033829032

SN - 1001-604X

VL - 18

SP - 533

EP - 536

JO - Chinese Journal of Chemistry

JF - Chinese Journal of Chemistry

IS - 4

ER -

Separation of chiral phosphorus compounds on the substituted β-cyclodextrin stationary phase in normal-phase liquid chromatography

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this