Separation of chiral phosphorus compounds on the substituted β-cyclodextrin stationary phase in normal-phase liquid chromatography

H. Chen, X. Y. Lu, R. Y. Gao, Jia Zhou, Q. S. Wang

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The separation of enantiomers of a series of eighteen novel nitrogen mustard linked phosphoryl diamide derivatives was investigated on the prepared phenyl carbamate derivative β-cyclodextrin bonded phase in normal-phase HPLC. Some of the enantiomers could be separated in baseline. The chiral recognition mechanism was also suggested for the separation of chiral phosphorus organic compound.

Original languageEnglish (US)
Pages (from-to)533-536
Number of pages4
JournalChinese Journal of Chemistry
Volume18
Issue number4
StatePublished - 2000
Externally publishedYes

Fingerprint

Phosphorus Compounds
Enantiomers
Liquid chromatography
Cyclodextrins
Phenylcarbamates
Diamide
Mechlorethamine
Organic compounds
Phosphorus
Derivatives

Keywords

  • β-cyclodextrin
  • Chiral stationary phase
  • Nitrogen mustard linked phosphoryl diamide derivatives
  • Normal-phase LC

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Separation of chiral phosphorus compounds on the substituted β-cyclodextrin stationary phase in normal-phase liquid chromatography. / Chen, H.; Lu, X. Y.; Gao, R. Y.; Zhou, Jia; Wang, Q. S.

In: Chinese Journal of Chemistry, Vol. 18, No. 4, 2000, p. 533-536.

Research output: Contribution to journalArticle

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AU - Zhou, Jia

AU - Wang, Q. S.

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