Septic shock

Pathogenesis and treatment

Leticia Castillo, Melchor Sanchez

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Septic shock is the host's inflammatory response to infection. There are multiple endogenous mediators responsible for the pathogenesis of septic shock. Cytokines, nitric oxide and prostaglandins are some of the major mediators. The term sepsis syndrome allows for an earlier diagnosis and treatment. Management of septic shock is focused in maintaining hemodynamic stability and an adequate oxygen delivery and utilization. Careful attention to each organ-system is of paramount importance to prevent complications and improve outcome. Experimental therapies to modulate the inflammatory response are promising.

Original languageEnglish (US)
Pages (from-to)367-379
Number of pages13
JournalThe Indian Journal of Pediatrics
Volume60
Issue number3
DOIs
StatePublished - May 1 1993
Externally publishedYes

Fingerprint

Septic Shock
Systemic Inflammatory Response Syndrome
Investigational Therapies
Prostaglandins
Early Diagnosis
Nitric Oxide
Therapeutics
Hemodynamics
Cytokines
Oxygen
Infection

Keywords

  • Critically ill
  • Sepsis syndrome
  • Septic shock

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Septic shock : Pathogenesis and treatment. / Castillo, Leticia; Sanchez, Melchor.

In: The Indian Journal of Pediatrics, Vol. 60, No. 3, 01.05.1993, p. 367-379.

Research output: Contribution to journalArticle

Castillo, Leticia ; Sanchez, Melchor. / Septic shock : Pathogenesis and treatment. In: The Indian Journal of Pediatrics. 1993 ; Vol. 60, No. 3. pp. 367-379.
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