Sequelae to acromegaly

Reversibility with treatment of the primary disease

Steven Lieberman, A. R. Hoffman

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Acromegalic patients suffer from a number of cardiovascular, metabolic, and rheumatologic problems, and they may also have an increased incidence of malignancy. We reviewed the literature concerning the reversibility of acromegalic complications. Hypertension, myorcardial hypertrophy, left ventricular dysfunction and some rheumatologic abnormalities often continue despite successful treatment of the acromegaly. In contrast, glucose intolerance, soft tissue changes, and carpal tunnel syndrome usually resolve when the acromegaly is cured. Studies of the incidence and mortality of cancer in acromegaly are conflicting, but several suggest an increased incidence of colorectal cancer.

Original languageEnglish (US)
Pages (from-to)313-318
Number of pages6
JournalHormone and Metabolic Research
Volume22
Issue number6
StatePublished - 1990
Externally publishedYes

Fingerprint

Acromegaly
Tunnels
Tissue
Glucose
Carpal Tunnel Syndrome
Glucose Intolerance
Incidence
Left Ventricular Dysfunction
Hypertrophy
Colorectal Neoplasms
Neoplasms
Cohort Studies
Therapeutics
Hypertension
Mortality

Keywords

  • acromegaly
  • cardiomyopathy
  • carpal tunnel syndrome
  • colorectal cancer
  • diabetes mellitus
  • hypertension
  • malignancy
  • osteoarthritis
  • ventricular hypertrophy

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology

Cite this

Sequelae to acromegaly : Reversibility with treatment of the primary disease. / Lieberman, Steven; Hoffman, A. R.

In: Hormone and Metabolic Research, Vol. 22, No. 6, 1990, p. 313-318.

Research output: Contribution to journalArticle

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