Serotoninergic and noradrenergic projections to the ventral posterolateral nucleus of the monkey thalamus

K. N. Westlund, L. S. Sorkin, D. G. Ferrington, S. M. Carlton, H. H. Willcockson, W. D. Willis

    Research output: Contribution to journalArticle

    30 Citations (Scopus)

    Abstract

    In the present study, serotoninergic and noradrenergic varicosities were identified in the ventral posterolateral nucleus of the macaque monkey. Monoaminergic neurons projecting to the ventral posterolateral nucleus of the thalamus were identified by using retrograde labeling with horseradish peroxidase combined with immunocytochemical staining for serotonin or dopamine-β-hydroxylase. The midbrain nucleus raphe dorsalis was the major site of origin for neurons providing a serotoninergic projection to the ventral posterolateral nucleus. A few retrogradely labeled serotonin-containing neurons were also observed in the central superior and the raphe pontis nuclei. Noradrenergic cells with projections to the thalamus were primarily located in the nucleus locus coeruleus with some projection neurons in the nucleus subcoeruleus, and the A5 catecholamine cell group of the pons.

    Original languageEnglish (US)
    Pages (from-to)197-207
    Number of pages11
    JournalJournal of Comparative Neurology
    Volume295
    Issue number2
    StatePublished - 1990

    Fingerprint

    Ventral Thalamic Nuclei
    Thalamus
    Haplorhini
    Neurons
    Serotonin
    Locus Coeruleus
    Pons
    Macaca
    Horseradish Peroxidase
    Mesencephalon
    Mixed Function Oxygenases
    Catecholamines
    Dopamine
    Staining and Labeling

    Keywords

    • dopamine-beta-hydroxylase
    • dorsal raphe
    • immunocytochemistry
    • locus coeruleus
    • primate

    ASJC Scopus subject areas

    • Neuroscience(all)

    Cite this

    Westlund, K. N., Sorkin, L. S., Ferrington, D. G., Carlton, S. M., Willcockson, H. H., & Willis, W. D. (1990). Serotoninergic and noradrenergic projections to the ventral posterolateral nucleus of the monkey thalamus. Journal of Comparative Neurology, 295(2), 197-207.

    Serotoninergic and noradrenergic projections to the ventral posterolateral nucleus of the monkey thalamus. / Westlund, K. N.; Sorkin, L. S.; Ferrington, D. G.; Carlton, S. M.; Willcockson, H. H.; Willis, W. D.

    In: Journal of Comparative Neurology, Vol. 295, No. 2, 1990, p. 197-207.

    Research output: Contribution to journalArticle

    Westlund, KN, Sorkin, LS, Ferrington, DG, Carlton, SM, Willcockson, HH & Willis, WD 1990, 'Serotoninergic and noradrenergic projections to the ventral posterolateral nucleus of the monkey thalamus', Journal of Comparative Neurology, vol. 295, no. 2, pp. 197-207.
    Westlund KN, Sorkin LS, Ferrington DG, Carlton SM, Willcockson HH, Willis WD. Serotoninergic and noradrenergic projections to the ventral posterolateral nucleus of the monkey thalamus. Journal of Comparative Neurology. 1990;295(2):197-207.
    Westlund, K. N. ; Sorkin, L. S. ; Ferrington, D. G. ; Carlton, S. M. ; Willcockson, H. H. ; Willis, W. D. / Serotoninergic and noradrenergic projections to the ventral posterolateral nucleus of the monkey thalamus. In: Journal of Comparative Neurology. 1990 ; Vol. 295, No. 2. pp. 197-207.
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