Serum ferritin assay and bone-marrow iron stores in patients on maintenance hemodialysis

J. D. Bell, W. R. Kincaid, R. G. Morgan, H. Bunce IIIrd, J. B. Alperin, H. E. Sarles, A. R. Remmers

Research output: Contribution to journalArticle

57 Citations (Scopus)

Abstract

Fifty five patients on maintenance hemodialysis underwent bone marrow aspirations for evaluation of iron stores that were to be compared to concomitant measurements of hematocrit, red blood cell volume, serum iron concentration, total iron binding capacity, transferrin saturation, and serum ferritin concentration. In 42 patients (76.4%), the bone-marrow iron stores were found to be absent or deficient. Mean hematocrit for the total group was 26.4%, and red blood cell volume measurement showed a mean value of 41.1% of predicted normal. Results also indicated that serum ferritin was the best predictor of iron storage levels, with diagnostic thresholds of 80 to 350 ng/ml derived from statistical analysis of the data. Other hematologic parameters studied had significantly less correlation with bone-marrow iron stores.

Original languageEnglish (US)
Pages (from-to)237-241
Number of pages5
JournalKidney International
Volume17
Issue number2
StatePublished - 1980
Externally publishedYes

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Ferritins
Renal Dialysis
Iron
Bone Marrow
Maintenance
Serum
Blood Volume
Cell Size
Hematocrit
Erythrocytes
Statistical Data Interpretation
Transferrin

ASJC Scopus subject areas

  • Nephrology

Cite this

Bell, J. D., Kincaid, W. R., Morgan, R. G., Bunce IIIrd, H., Alperin, J. B., Sarles, H. E., & Remmers, A. R. (1980). Serum ferritin assay and bone-marrow iron stores in patients on maintenance hemodialysis. Kidney International, 17(2), 237-241.

Serum ferritin assay and bone-marrow iron stores in patients on maintenance hemodialysis. / Bell, J. D.; Kincaid, W. R.; Morgan, R. G.; Bunce IIIrd, H.; Alperin, J. B.; Sarles, H. E.; Remmers, A. R.

In: Kidney International, Vol. 17, No. 2, 1980, p. 237-241.

Research output: Contribution to journalArticle

Bell, JD, Kincaid, WR, Morgan, RG, Bunce IIIrd, H, Alperin, JB, Sarles, HE & Remmers, AR 1980, 'Serum ferritin assay and bone-marrow iron stores in patients on maintenance hemodialysis', Kidney International, vol. 17, no. 2, pp. 237-241.
Bell JD, Kincaid WR, Morgan RG, Bunce IIIrd H, Alperin JB, Sarles HE et al. Serum ferritin assay and bone-marrow iron stores in patients on maintenance hemodialysis. Kidney International. 1980;17(2):237-241.
Bell, J. D. ; Kincaid, W. R. ; Morgan, R. G. ; Bunce IIIrd, H. ; Alperin, J. B. ; Sarles, H. E. ; Remmers, A. R. / Serum ferritin assay and bone-marrow iron stores in patients on maintenance hemodialysis. In: Kidney International. 1980 ; Vol. 17, No. 2. pp. 237-241.
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