Serum ionized magnesium changes during and immediately after liver transplantation

V. Douzdjian, D. Filos, A. O. Okorodudu

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Alterations in magnesium (Mg) homeostasis during and after orthotopic liver transplantation are common. The purpose of this study is to compare total Mg (TMg), calculated ionized Mg (cMg++) and measured ionized Mg (mMg++) during and immediately following liver transplantation. The newly developed first generation ion selective electrode analyzer, AVL 988-4, was used to measure mMg++ in 63 serum samples from 3 transplant recipients and 48 serum samples from 48 healthy volunteers. Analysis was divided into intraoperative (stages 1 to 3) and postoperative periods. Decreased TMg, cMg++ and mMg++ levels were observed intraoperatively and >2 weeks postoperatively. The cMg++ levels were consistently higher than mMg++, presumably owing to the fact that the equation used for the calculation does not take complex-Mg++ into account. A better correlation was observed between mMg++ and cMg++ in the transplant group (r = 0.87 to 0.99) compared to controls (r = 0.74). The usefulness of direct measurement of Mg++ in liver transplantation remains to be determined.

Original languageEnglish (US)
Pages (from-to)297-305
Number of pages9
JournalAnnals of Clinical and Laboratory Science
Issue number4
StatePublished - 1995

ASJC Scopus subject areas

  • General Medicine


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