Session II: Pulmonary injury: Pulmonary circulation and burns and trauma

David Herndon, Daniel L. Trarer

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The lung is a critical organ in victims of thermal injury or multiple trauma since the blood that drains injured organs circulates through the pulmonary circulation before passing through any other organ. The lung therefore will receive the first volley of cytotoxins released postinjury. In addition to being a target of injury, the lung may also contribute to the injury of systemic organs. This injury may be the result of a reduced delivery of oxygenated blood or the direct release of cytotoxins into the systemic circulation. The injury to the lung may be to the pulmonary microvasculature or the airway. The bronchial circulation responds to injury by a marked elevation in its blood flow and microvascular permeability. These latter effects may be important in mediating the changes which occur in the lung parenchyma.

Original languageEnglish (US)
Pages (from-to)S41-S44
JournalJournal of Trauma - Injury, Infection and Critical Care
Volume30
Issue number12
StatePublished - 1990
Externally publishedYes

Fingerprint

Pulmonary Circulation
Lung Injury
Burns
Lung
Cytotoxins
Wounds and Injuries
Multiple Trauma
Capillary Permeability
Microvessels
Hot Temperature

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Surgery

Cite this

Session II : Pulmonary injury: Pulmonary circulation and burns and trauma. / Herndon, David; Trarer, Daniel L.

In: Journal of Trauma - Injury, Infection and Critical Care, Vol. 30, No. 12, 1990, p. S41-S44.

Research output: Contribution to journalArticle

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