Abstract
The lung is a critical organ in victims of thermal injury or multiple trauma since the blood that drains injured organs circulates through the pulmonary circulation before passing through any other organ. The lung therefore will receive the first volley of cytotoxins released postinjury. In addition to being a target of injury, the lung may also contribute to the injury of systemic organs. This injury may be the result of a reduced delivery of oxygenated blood or the direct release of cytotoxins into the systemic circulation. The injury to the lung may be to the pulmonary microvasculature or the airway. The bronchial circulation responds to injury by a marked elevation in its blood flow and microvascular permeability. These latter effects may be important in mediating the changes which occur in the lung parenchyma.
| Original language | English (US) |
|---|---|
| Pages (from-to) | S41-S44 |
| Journal | Journal of Trauma - Injury, Infection and Critical Care |
| Volume | 30 |
| Issue number | 12 |
| State | Published - 1990 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Critical Care and Intensive Care Medicine
- Surgery
Cite this
Session II : Pulmonary injury: Pulmonary circulation and burns and trauma. / Herndon, David; Trarer, Daniel L.
In: Journal of Trauma - Injury, Infection and Critical Care, Vol. 30, No. 12, 1990, p. S41-S44.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Session II
T2 - Pulmonary injury: Pulmonary circulation and burns and trauma
AU - Herndon, David
AU - Trarer, Daniel L.
PY - 1990
Y1 - 1990
N2 - The lung is a critical organ in victims of thermal injury or multiple trauma since the blood that drains injured organs circulates through the pulmonary circulation before passing through any other organ. The lung therefore will receive the first volley of cytotoxins released postinjury. In addition to being a target of injury, the lung may also contribute to the injury of systemic organs. This injury may be the result of a reduced delivery of oxygenated blood or the direct release of cytotoxins into the systemic circulation. The injury to the lung may be to the pulmonary microvasculature or the airway. The bronchial circulation responds to injury by a marked elevation in its blood flow and microvascular permeability. These latter effects may be important in mediating the changes which occur in the lung parenchyma.
AB - The lung is a critical organ in victims of thermal injury or multiple trauma since the blood that drains injured organs circulates through the pulmonary circulation before passing through any other organ. The lung therefore will receive the first volley of cytotoxins released postinjury. In addition to being a target of injury, the lung may also contribute to the injury of systemic organs. This injury may be the result of a reduced delivery of oxygenated blood or the direct release of cytotoxins into the systemic circulation. The injury to the lung may be to the pulmonary microvasculature or the airway. The bronchial circulation responds to injury by a marked elevation in its blood flow and microvascular permeability. These latter effects may be important in mediating the changes which occur in the lung parenchyma.
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UR - http://www.scopus.com/inward/citedby.url?scp=84938038288&partnerID=8YFLogxK
M3 - Article
VL - 30
SP - S41-S44
JO - Journal of Trauma and Acute Care Surgery
JF - Journal of Trauma and Acute Care Surgery
SN - 2163-0755
IS - 12
ER -