Severe ciprofloxacin-associated pseudomembranous colitis in an eight-year-old child

Carlos A. Angel; Justtin Green; Leonard Swischuk; Janak Patel

doi:10.1016/j.jpedsurg.2004.06.028

Severe ciprofloxacin-associated pseudomembranous colitis in an eight-year-old child

Carlos A. Angel, Justtin Green, Leonard Swischuk, Janak Patel

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Clostridium difficile is the principal cause of antibiotic-associated diarrhea and pseudomembranous enterocolitis in children. A case of severe pseudomembranous colitis developing in an 8-year-old child who had received oral ciprofloxacin therapy as part of an investigational protocol is presented. The safety and efficacy of fluoroquinolones in children has not yet been established. Use of these antibiotics in children outside investigational protocols ("off-label" use) as oral antipseudomonas agents is discouraged.

Original language	English (US)
Pages (from-to)	1590-1592
Number of pages	3
Journal	Journal of Pediatric Surgery
Volume	39
Issue number	10
DOIs	https://doi.org/10.1016/j.jpedsurg.2004.06.028
State	Published - Oct 2004

Keywords

Clostridium difficile
Pseudomembranous colitis
antibiotic-induced diarrhea
ciprofloxacin
fluoroquinolones

ASJC Scopus subject areas

Surgery
Pediatrics, Perinatology, and Child Health

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10.1016/j.jpedsurg.2004.06.028

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abstract = "Clostridium difficile is the principal cause of antibiotic-associated diarrhea and pseudomembranous enterocolitis in children. A case of severe pseudomembranous colitis developing in an 8-year-old child who had received oral ciprofloxacin therapy as part of an investigational protocol is presented. The safety and efficacy of fluoroquinolones in children has not yet been established. Use of these antibiotics in children outside investigational protocols ({"}off-label{"} use) as oral antipseudomonas agents is discouraged.",

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AU - Green, Justtin

AU - Swischuk, Leonard

AU - Patel, Janak

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AB - Clostridium difficile is the principal cause of antibiotic-associated diarrhea and pseudomembranous enterocolitis in children. A case of severe pseudomembranous colitis developing in an 8-year-old child who had received oral ciprofloxacin therapy as part of an investigational protocol is presented. The safety and efficacy of fluoroquinolones in children has not yet been established. Use of these antibiotics in children outside investigational protocols ("off-label" use) as oral antipseudomonas agents is discouraged.

KW - Clostridium difficile

KW - Pseudomembranous colitis

KW - antibiotic-induced diarrhea

KW - ciprofloxacin

KW - fluoroquinolones

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Severe ciprofloxacin-associated pseudomembranous colitis in an eight-year-old child

Abstract

Keywords

ASJC Scopus subject areas

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