Severe fever with thrombocytopenia syndrome, Shandong Province, China, 2011

Hong Ling Wen, Li Zhao, Shenyong Zhai, Yuanyuan Chi, Feng Cui, Dongxu Wang, Ling Wang, Zhiyu Wang, Qian Wang, Shoufeng Zhang, Yan Liu, Hao Yu, Xue Jie Yu

Research output: Contribution to journalArticlepeer-review

37 Scopus citations


Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease in China. The incidence and clinical and laboratory characteristics of SFTS are not clearly defined. During May 22-October 2, 2011, a total of 24 patients with fever, thrombocytopenia, and leukopenia were clinically diagnosed as having SFTS in Yiyuan County, Shandong Province, China. We conducted laboratory tests for these SFTS patients. SFTS virus (SFTSV) infection was confirmed in 22 patients by using reverse transcription PCR and ELISA by acute-phase and convalescent-phase serum samples. Clinical and laboratory manifestations included fever (100%), gastrointestinal symptoms (91%), myalgia (55%), chills (41%), thrombocytopenia (100%), and leukopenia (95%).

Original languageEnglish (US)
Pages (from-to)1-5
Number of pages5
JournalEmerging infectious diseases
Issue number1
StatePublished - 2014

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases


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