Severe sepsis during pregnancy

Luis Pacheco, George Saade, Gary Hankins

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Severe sepsis is a major cause of mortality among critically ill patients. Early recognition accompanied by early initiation of broad-spectrum antibiotics with source control and fluid resuscitation improves outcomes. Hemodynamic resuscitation starts with fluid therapy followed by vasopressors if necessary. Cases refractory to first-line vasopressors (norepinephrine) will require second-line vasopressors (epinephrine or vasopressin) and low-dose steroid therapy. Resuscitation goals should include optimization of central venous oxygenation and serum lactate.

Original languageEnglish
Pages (from-to)827-834
Number of pages8
JournalClinical Obstetrics and Gynecology
Volume57
Issue number4
StatePublished - 2014

Fingerprint

Resuscitation
Sepsis
Pregnancy
Fluid Therapy
Vasopressins
Critical Illness
Epinephrine
Lactic Acid
Norepinephrine
Hemodynamics
Steroids
Anti-Bacterial Agents
Mortality
Serum
Therapeutics

Keywords

  • Pregnancy
  • Sepsis
  • Septic shock

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Severe sepsis during pregnancy. / Pacheco, Luis; Saade, George; Hankins, Gary.

In: Clinical Obstetrics and Gynecology, Vol. 57, No. 4, 2014, p. 827-834.

Research output: Contribution to journalArticle

Pacheco, Luis ; Saade, George ; Hankins, Gary. / Severe sepsis during pregnancy. In: Clinical Obstetrics and Gynecology. 2014 ; Vol. 57, No. 4. pp. 827-834.
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