Shedding UV Light on Alternative Splicing

Matthew S. Marengo, Mariano A. Garcia-Blanco

Research output: Contribution to journalShort surveypeer-review

2 Scopus citations

Abstract

After DNA damage, cells modulate pre-messenger RNA (pre-mRNA) splicing to induce an anti- or proapoptotic response. In this issue, Muñoz et al. (2009) uncover a cotranscriptional mechanism for activating alternative pre-mRNA splicing after ultraviolet irradiation that depends unexpectedly on hyperphosphorylation of the RNA polymerase II C-terminal domain and decreased rates of transcription elongation.

Original languageEnglish (US)
Pages (from-to)600-602
Number of pages3
JournalCell
Volume137
Issue number4
DOIs
StatePublished - May 15 2009

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Fingerprint Dive into the research topics of 'Shedding UV Light on Alternative Splicing'. Together they form a unique fingerprint.

Cite this