Short report: Rickettsia felis outer membrane protein A: A potential tool for diagnosis of patients with flea-borne spotted fever

Jorge E. Zavala-Castro, Karla R. Dzul-Rosado, Juan José Arias León, David Walker, Jorge E. Zavala-Velázquez

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Rickettsia felis infection in humans has been detected worldwide, causing an illness that could be confused with other viral and bacterial infections such as dengue fever. Despite the high incidence of infection in humans, reservoirs, and vectors, the definitive diagnosis of R. felis infection currently requires polymerase chain reaction and sequencing because its antigens are closely related to other rickettsiae, making serologic diagnosis problematic. In this work, we report the immune reactivity of sera from four patients infected with R. felis with recombinant peptides representing regions of outer membrane protein A of R. felis.

Original languageEnglish (US)
Pages (from-to)903-906
Number of pages4
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume79
Issue number6
StatePublished - Dec 2008

Fingerprint

Rickettsia felis
Siphonaptera
Fever
Rickettsia Infections
Rickettsia
Dengue
Virus Diseases
Bacterial Infections
Immune Sera
Antigens
Polymerase Chain Reaction
Peptides
OMPA outer membrane proteins
Incidence
Infection

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases
  • Virology

Cite this

Short report : Rickettsia felis outer membrane protein A: A potential tool for diagnosis of patients with flea-borne spotted fever. / Zavala-Castro, Jorge E.; Dzul-Rosado, Karla R.; León, Juan José Arias; Walker, David; Zavala-Velázquez, Jorge E.

In: American Journal of Tropical Medicine and Hygiene, Vol. 79, No. 6, 12.2008, p. 903-906.

Research output: Contribution to journalArticle

Zavala-Castro, Jorge E. ; Dzul-Rosado, Karla R. ; León, Juan José Arias ; Walker, David ; Zavala-Velázquez, Jorge E. / Short report : Rickettsia felis outer membrane protein A: A potential tool for diagnosis of patients with flea-borne spotted fever. In: American Journal of Tropical Medicine and Hygiene. 2008 ; Vol. 79, No. 6. pp. 903-906.
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