Short-term β-hydroxy-β-methylbutyrate supplementation does not reduce symptoms of eccentric muscle damage

Douglas Paddon-Jones, A. Keech, D. Jenkins

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

Purpose: We examined the effects of short-term β-hydroxy-β-methylbutyrate (HMB) supplementation on symptoms of muscle damage following an acute bout of eccentric exercise. Methods: Non-resistance trained subjects were randomly assigned to a HMB supplement group (HMB, 40mg/kg bodyweight/day, n = 8) or placebo group (CON, n = 9). Supplementation commenced 6 days prior to a bout of 24 maximal isokinetic eccentric contractions of the elbow flexors and continued throughout post-testing. Muscle soreness, upper arm girth, and torque measures were assessed pre-exercise, 15 min post-exercise, and 1, 2, 3, 4, 7, and 10 days post-exercise. Results: No pre-test differences between HMB and CON groups were identified, and both performed a similar amount of eccentric work during the main eccentric exercise bout (p > .05). HMB supplementation had no effect on swelling, muscle soreness, or torque following the damaging eccentric exercise bout (p > .05). Conclusion: Compared to a placebo condition, short-term supplementation with 40mg/kg bodyweight/day of HMB had no beneficial effect on a range of symptoms associated with eccentric muscle damage. If HMB can produce an ergogenic response, a longer pre-exercise supplementation period may be necessary.

Original languageEnglish (US)
Pages (from-to)442-450
Number of pages9
JournalInternational Journal of Sport Nutrition
Volume11
Issue number4
StatePublished - 2001
Externally publishedYes

Fingerprint

Myalgia
Torque
signs and symptoms (animals and humans)
exercise
Placebos
Muscles
muscles
Elbow
Arm
torque
placebos
body weight
elbows
girth
testing

Keywords

  • DOMS
  • Exercise
  • HMB
  • Recovery

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Endocrinology
  • Public Health, Environmental and Occupational Health
  • Food Science

Cite this

Short-term β-hydroxy-β-methylbutyrate supplementation does not reduce symptoms of eccentric muscle damage. / Paddon-Jones, Douglas; Keech, A.; Jenkins, D.

In: International Journal of Sport Nutrition, Vol. 11, No. 4, 2001, p. 442-450.

Research output: Contribution to journalArticle

@article{1dba03add55b415a8070df1b79b262f9,
title = "Short-term β-hydroxy-β-methylbutyrate supplementation does not reduce symptoms of eccentric muscle damage",
abstract = "Purpose: We examined the effects of short-term β-hydroxy-β-methylbutyrate (HMB) supplementation on symptoms of muscle damage following an acute bout of eccentric exercise. Methods: Non-resistance trained subjects were randomly assigned to a HMB supplement group (HMB, 40mg/kg bodyweight/day, n = 8) or placebo group (CON, n = 9). Supplementation commenced 6 days prior to a bout of 24 maximal isokinetic eccentric contractions of the elbow flexors and continued throughout post-testing. Muscle soreness, upper arm girth, and torque measures were assessed pre-exercise, 15 min post-exercise, and 1, 2, 3, 4, 7, and 10 days post-exercise. Results: No pre-test differences between HMB and CON groups were identified, and both performed a similar amount of eccentric work during the main eccentric exercise bout (p > .05). HMB supplementation had no effect on swelling, muscle soreness, or torque following the damaging eccentric exercise bout (p > .05). Conclusion: Compared to a placebo condition, short-term supplementation with 40mg/kg bodyweight/day of HMB had no beneficial effect on a range of symptoms associated with eccentric muscle damage. If HMB can produce an ergogenic response, a longer pre-exercise supplementation period may be necessary.",
keywords = "DOMS, Exercise, HMB, Recovery",
author = "Douglas Paddon-Jones and A. Keech and D. Jenkins",
year = "2001",
language = "English (US)",
volume = "11",
pages = "442--450",
journal = "International Journal of Sport Nutrition and Exercise Metabolism",
issn = "1526-484X",
publisher = "Human Kinetics Publishers Inc.",
number = "4",

}

TY - JOUR

T1 - Short-term β-hydroxy-β-methylbutyrate supplementation does not reduce symptoms of eccentric muscle damage

AU - Paddon-Jones, Douglas

AU - Keech, A.

AU - Jenkins, D.

PY - 2001

Y1 - 2001

N2 - Purpose: We examined the effects of short-term β-hydroxy-β-methylbutyrate (HMB) supplementation on symptoms of muscle damage following an acute bout of eccentric exercise. Methods: Non-resistance trained subjects were randomly assigned to a HMB supplement group (HMB, 40mg/kg bodyweight/day, n = 8) or placebo group (CON, n = 9). Supplementation commenced 6 days prior to a bout of 24 maximal isokinetic eccentric contractions of the elbow flexors and continued throughout post-testing. Muscle soreness, upper arm girth, and torque measures were assessed pre-exercise, 15 min post-exercise, and 1, 2, 3, 4, 7, and 10 days post-exercise. Results: No pre-test differences between HMB and CON groups were identified, and both performed a similar amount of eccentric work during the main eccentric exercise bout (p > .05). HMB supplementation had no effect on swelling, muscle soreness, or torque following the damaging eccentric exercise bout (p > .05). Conclusion: Compared to a placebo condition, short-term supplementation with 40mg/kg bodyweight/day of HMB had no beneficial effect on a range of symptoms associated with eccentric muscle damage. If HMB can produce an ergogenic response, a longer pre-exercise supplementation period may be necessary.

AB - Purpose: We examined the effects of short-term β-hydroxy-β-methylbutyrate (HMB) supplementation on symptoms of muscle damage following an acute bout of eccentric exercise. Methods: Non-resistance trained subjects were randomly assigned to a HMB supplement group (HMB, 40mg/kg bodyweight/day, n = 8) or placebo group (CON, n = 9). Supplementation commenced 6 days prior to a bout of 24 maximal isokinetic eccentric contractions of the elbow flexors and continued throughout post-testing. Muscle soreness, upper arm girth, and torque measures were assessed pre-exercise, 15 min post-exercise, and 1, 2, 3, 4, 7, and 10 days post-exercise. Results: No pre-test differences between HMB and CON groups were identified, and both performed a similar amount of eccentric work during the main eccentric exercise bout (p > .05). HMB supplementation had no effect on swelling, muscle soreness, or torque following the damaging eccentric exercise bout (p > .05). Conclusion: Compared to a placebo condition, short-term supplementation with 40mg/kg bodyweight/day of HMB had no beneficial effect on a range of symptoms associated with eccentric muscle damage. If HMB can produce an ergogenic response, a longer pre-exercise supplementation period may be necessary.

KW - DOMS

KW - Exercise

KW - HMB

KW - Recovery

UR - http://www.scopus.com/inward/record.url?scp=0035670865&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035670865&partnerID=8YFLogxK

M3 - Article

C2 - 11915779

AN - SCOPUS:0035670865

VL - 11

SP - 442

EP - 450

JO - International Journal of Sport Nutrition and Exercise Metabolism

JF - International Journal of Sport Nutrition and Exercise Metabolism

SN - 1526-484X

IS - 4

ER -