Side-effect reduction by use of drugs that bind to separate but equivalent binding sites

Gerald Ehrenstein, Li-Yen Huang

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

If two drugs cause the same molecular effect by binding to separate noncompetitive binding sites, therapy with a mixture of the two drugs can provide a given desired effect with a lower level of side effects than therapy with either drug alone.

Original languageEnglish (US)
Pages (from-to)1365-1366
Number of pages2
JournalScience
Volume214
Issue number4527
StatePublished - 1981
Externally publishedYes

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Binding Sites
Pharmaceutical Preparations
Therapeutics

ASJC Scopus subject areas

  • General

Cite this

Side-effect reduction by use of drugs that bind to separate but equivalent binding sites. / Ehrenstein, Gerald; Huang, Li-Yen.

In: Science, Vol. 214, No. 4527, 1981, p. 1365-1366.

Research output: Contribution to journalArticle

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