Silver-coated nylon dressing plus active DC microcurrent for healing of autogenous skin donor sites

Edward W. Malin, Chaya M. Galin, Kimberley F. Lairet, Todd F. Huzar, James F. Williams, Evan M. Renz, Steven Wolf, Leopoldo C. Cancio

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Introduction: Burn wounds are a significant cause of morbidity and mortality, and improved outcomes are demonstrated with early closure of both primary burn wounds and skin donor sites. Thus, technology that decreases the healing time of burns and donor sites would be potentially lifesaving. We present the results of a single-center, prospective, double-blinded, randomized controlled trial to evaluate the efficacy of silver-coated dressing with active microcurrent in comparison to silver-coated dressing with sham microcurrent on wound-closure time for autogenous skin donor sites. Methods: Four hundred five patients were screened for treatment of their donor sites using a silver-coated nylon dressing with either sham or active microcurrent stimulation. Thirty patients were enrolled in the study and then randomized. Of these, 5 patients were removed from analysis due to protocol deviations. Differences in time-to-closure were analyzed using Kaplan-Meier analysis and the proportional hazard regression model. Subjective verbal pain rating scores (0-10; 0, no pain; 10, worst pain) were also recorded. All devices were blinded and programmed at an outside facility, so that every patient had either an active or sham device. The study was unblinded only after the final patient's donor site had healed. All patients achieved donor-site healing before postoperative day 20. The 14 patients in the active microcurrent group [mean, 10.8 (2.9) days; range, 7-15 days] experienced no difference in time to wound healing as compared to the remaining patients in the sham microcurrent group [mean, 11.1 (2.0) days; range, 8-14 days; P = 0.75]. There were no differences in pain from one group compared to the other. None of the donor sites exhibited clinical signs of infection. Conclusions: In a sample size of 25 burn patients, the addition of direct microcurrent to silver-nylon dressings did not decrease time to wound closure of skin donor sites, and it did not show a difference in reported pain levels.

Original languageEnglish (US)
Pages (from-to)481-484
Number of pages4
JournalAnnals of Plastic Surgery
Volume71
Issue number5
DOIs
StatePublished - Nov 1 2013
Externally publishedYes

Fingerprint

Nylons
Bandages
Silver
Tissue Donors
Skin
Pain
Wounds and Injuries
Equipment and Supplies
Kaplan-Meier Estimate
Burns
Proportional Hazards Models
Sample Size
Wound Healing
Randomized Controlled Trials
Technology
Morbidity
Mortality
Infection

Keywords

  • bandages
  • Burns
  • electric stimulation therapy
  • silver
  • skin transplantation
  • wound healing

ASJC Scopus subject areas

  • Surgery

Cite this

Malin, E. W., Galin, C. M., Lairet, K. F., Huzar, T. F., Williams, J. F., Renz, E. M., ... Cancio, L. C. (2013). Silver-coated nylon dressing plus active DC microcurrent for healing of autogenous skin donor sites. Annals of Plastic Surgery, 71(5), 481-484. https://doi.org/10.1097/SAP.0b013e31829d2311

Silver-coated nylon dressing plus active DC microcurrent for healing of autogenous skin donor sites. / Malin, Edward W.; Galin, Chaya M.; Lairet, Kimberley F.; Huzar, Todd F.; Williams, James F.; Renz, Evan M.; Wolf, Steven; Cancio, Leopoldo C.

In: Annals of Plastic Surgery, Vol. 71, No. 5, 01.11.2013, p. 481-484.

Research output: Contribution to journalArticle

Malin, EW, Galin, CM, Lairet, KF, Huzar, TF, Williams, JF, Renz, EM, Wolf, S & Cancio, LC 2013, 'Silver-coated nylon dressing plus active DC microcurrent for healing of autogenous skin donor sites', Annals of Plastic Surgery, vol. 71, no. 5, pp. 481-484. https://doi.org/10.1097/SAP.0b013e31829d2311
Malin, Edward W. ; Galin, Chaya M. ; Lairet, Kimberley F. ; Huzar, Todd F. ; Williams, James F. ; Renz, Evan M. ; Wolf, Steven ; Cancio, Leopoldo C. / Silver-coated nylon dressing plus active DC microcurrent for healing of autogenous skin donor sites. In: Annals of Plastic Surgery. 2013 ; Vol. 71, No. 5. pp. 481-484.
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abstract = "Introduction: Burn wounds are a significant cause of morbidity and mortality, and improved outcomes are demonstrated with early closure of both primary burn wounds and skin donor sites. Thus, technology that decreases the healing time of burns and donor sites would be potentially lifesaving. We present the results of a single-center, prospective, double-blinded, randomized controlled trial to evaluate the efficacy of silver-coated dressing with active microcurrent in comparison to silver-coated dressing with sham microcurrent on wound-closure time for autogenous skin donor sites. Methods: Four hundred five patients were screened for treatment of their donor sites using a silver-coated nylon dressing with either sham or active microcurrent stimulation. Thirty patients were enrolled in the study and then randomized. Of these, 5 patients were removed from analysis due to protocol deviations. Differences in time-to-closure were analyzed using Kaplan-Meier analysis and the proportional hazard regression model. Subjective verbal pain rating scores (0-10; 0, no pain; 10, worst pain) were also recorded. All devices were blinded and programmed at an outside facility, so that every patient had either an active or sham device. The study was unblinded only after the final patient's donor site had healed. All patients achieved donor-site healing before postoperative day 20. The 14 patients in the active microcurrent group [mean, 10.8 (2.9) days; range, 7-15 days] experienced no difference in time to wound healing as compared to the remaining patients in the sham microcurrent group [mean, 11.1 (2.0) days; range, 8-14 days; P = 0.75]. There were no differences in pain from one group compared to the other. None of the donor sites exhibited clinical signs of infection. Conclusions: In a sample size of 25 burn patients, the addition of direct microcurrent to silver-nylon dressings did not decrease time to wound closure of skin donor sites, and it did not show a difference in reported pain levels.",
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AU - Galin, Chaya M.

AU - Lairet, Kimberley F.

AU - Huzar, Todd F.

AU - Williams, James F.

AU - Renz, Evan M.

AU - Wolf, Steven

AU - Cancio, Leopoldo C.

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N2 - Introduction: Burn wounds are a significant cause of morbidity and mortality, and improved outcomes are demonstrated with early closure of both primary burn wounds and skin donor sites. Thus, technology that decreases the healing time of burns and donor sites would be potentially lifesaving. We present the results of a single-center, prospective, double-blinded, randomized controlled trial to evaluate the efficacy of silver-coated dressing with active microcurrent in comparison to silver-coated dressing with sham microcurrent on wound-closure time for autogenous skin donor sites. Methods: Four hundred five patients were screened for treatment of their donor sites using a silver-coated nylon dressing with either sham or active microcurrent stimulation. Thirty patients were enrolled in the study and then randomized. Of these, 5 patients were removed from analysis due to protocol deviations. Differences in time-to-closure were analyzed using Kaplan-Meier analysis and the proportional hazard regression model. Subjective verbal pain rating scores (0-10; 0, no pain; 10, worst pain) were also recorded. All devices were blinded and programmed at an outside facility, so that every patient had either an active or sham device. The study was unblinded only after the final patient's donor site had healed. All patients achieved donor-site healing before postoperative day 20. The 14 patients in the active microcurrent group [mean, 10.8 (2.9) days; range, 7-15 days] experienced no difference in time to wound healing as compared to the remaining patients in the sham microcurrent group [mean, 11.1 (2.0) days; range, 8-14 days; P = 0.75]. There were no differences in pain from one group compared to the other. None of the donor sites exhibited clinical signs of infection. Conclusions: In a sample size of 25 burn patients, the addition of direct microcurrent to silver-nylon dressings did not decrease time to wound closure of skin donor sites, and it did not show a difference in reported pain levels.

AB - Introduction: Burn wounds are a significant cause of morbidity and mortality, and improved outcomes are demonstrated with early closure of both primary burn wounds and skin donor sites. Thus, technology that decreases the healing time of burns and donor sites would be potentially lifesaving. We present the results of a single-center, prospective, double-blinded, randomized controlled trial to evaluate the efficacy of silver-coated dressing with active microcurrent in comparison to silver-coated dressing with sham microcurrent on wound-closure time for autogenous skin donor sites. Methods: Four hundred five patients were screened for treatment of their donor sites using a silver-coated nylon dressing with either sham or active microcurrent stimulation. Thirty patients were enrolled in the study and then randomized. Of these, 5 patients were removed from analysis due to protocol deviations. Differences in time-to-closure were analyzed using Kaplan-Meier analysis and the proportional hazard regression model. Subjective verbal pain rating scores (0-10; 0, no pain; 10, worst pain) were also recorded. All devices were blinded and programmed at an outside facility, so that every patient had either an active or sham device. The study was unblinded only after the final patient's donor site had healed. All patients achieved donor-site healing before postoperative day 20. The 14 patients in the active microcurrent group [mean, 10.8 (2.9) days; range, 7-15 days] experienced no difference in time to wound healing as compared to the remaining patients in the sham microcurrent group [mean, 11.1 (2.0) days; range, 8-14 days; P = 0.75]. There were no differences in pain from one group compared to the other. None of the donor sites exhibited clinical signs of infection. Conclusions: In a sample size of 25 burn patients, the addition of direct microcurrent to silver-nylon dressings did not decrease time to wound closure of skin donor sites, and it did not show a difference in reported pain levels.

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