Simplified method for G6PD screening using blood collected on filter paper

P. A. Dow, M. B. Petteway, J. B. Alperin

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

A rapid screening method for detecting glucose 6 phosphate dehydrogenase (G6PD) deficiency is described. The method involves the collection of blood samples on filter paper and depends on the fluorescence of reduced nicotinamide adenine dinucleotide phosphate. Simple and inexpensive to perform, this test yields positive results when enzyme levels are less than 25% of normal, thus permitting the easy detection of hemizygous men and homozygous women with G6PD deficiency. This test may give positive results in some heterozygous female carriers.

Original languageEnglish (US)
Pages (from-to)333-336
Number of pages4
JournalAmerican journal of clinical pathology
Volume61
Issue number3
DOIs
StatePublished - Jan 1 1974

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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