Simplified method for G6PD screening using blood collected on filter paper

P. A. Dow, M. B. Petteway, J. B. Alperin

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A rapid screening method for detecting glucose 6 phosphate dehydrogenase (G6PD) deficiency is described. The method involves the collection of blood samples on filter paper and depends on the fluorescence of reduced nicotinamide adenine dinucleotide phosphate. Simple and inexpensive to perform, this test yields positive results when enzyme levels are less than 25% of normal, thus permitting the easy detection of hemizygous men and homozygous women with G6PD deficiency. This test may give positive results in some heterozygous female carriers.

Original languageEnglish (US)
Pages (from-to)333-336
Number of pages4
JournalAmerican Journal of Clinical Pathology
Volume61
Issue number3
StatePublished - 1974

Fingerprint

Glucosephosphate Dehydrogenase Deficiency
Glucosephosphate Dehydrogenase
NADP
Fluorescence
Enzymes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Simplified method for G6PD screening using blood collected on filter paper. / Dow, P. A.; Petteway, M. B.; Alperin, J. B.

In: American Journal of Clinical Pathology, Vol. 61, No. 3, 1974, p. 333-336.

Research output: Contribution to journalArticle

Dow, PA, Petteway, MB & Alperin, JB 1974, 'Simplified method for G6PD screening using blood collected on filter paper', American Journal of Clinical Pathology, vol. 61, no. 3, pp. 333-336.
Dow, P. A. ; Petteway, M. B. ; Alperin, J. B. / Simplified method for G6PD screening using blood collected on filter paper. In: American Journal of Clinical Pathology. 1974 ; Vol. 61, No. 3. pp. 333-336.
@article{bf2b647948f14205904165a0aff2f8b9,
title = "Simplified method for G6PD screening using blood collected on filter paper",
abstract = "A rapid screening method for detecting glucose 6 phosphate dehydrogenase (G6PD) deficiency is described. The method involves the collection of blood samples on filter paper and depends on the fluorescence of reduced nicotinamide adenine dinucleotide phosphate. Simple and inexpensive to perform, this test yields positive results when enzyme levels are less than 25{\%} of normal, thus permitting the easy detection of hemizygous men and homozygous women with G6PD deficiency. This test may give positive results in some heterozygous female carriers.",
author = "Dow, {P. A.} and Petteway, {M. B.} and Alperin, {J. B.}",
year = "1974",
language = "English (US)",
volume = "61",
pages = "333--336",
journal = "American Journal of Clinical Pathology",
issn = "0002-9173",
publisher = "American Society of Clinical Pathologists",
number = "3",

}

TY - JOUR

T1 - Simplified method for G6PD screening using blood collected on filter paper

AU - Dow, P. A.

AU - Petteway, M. B.

AU - Alperin, J. B.

PY - 1974

Y1 - 1974

N2 - A rapid screening method for detecting glucose 6 phosphate dehydrogenase (G6PD) deficiency is described. The method involves the collection of blood samples on filter paper and depends on the fluorescence of reduced nicotinamide adenine dinucleotide phosphate. Simple and inexpensive to perform, this test yields positive results when enzyme levels are less than 25% of normal, thus permitting the easy detection of hemizygous men and homozygous women with G6PD deficiency. This test may give positive results in some heterozygous female carriers.

AB - A rapid screening method for detecting glucose 6 phosphate dehydrogenase (G6PD) deficiency is described. The method involves the collection of blood samples on filter paper and depends on the fluorescence of reduced nicotinamide adenine dinucleotide phosphate. Simple and inexpensive to perform, this test yields positive results when enzyme levels are less than 25% of normal, thus permitting the easy detection of hemizygous men and homozygous women with G6PD deficiency. This test may give positive results in some heterozygous female carriers.

UR - http://www.scopus.com/inward/record.url?scp=0015972358&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0015972358&partnerID=8YFLogxK

M3 - Article

VL - 61

SP - 333

EP - 336

JO - American Journal of Clinical Pathology

JF - American Journal of Clinical Pathology

SN - 0002-9173

IS - 3

ER -