A rapid screening method for detecting glucose 6 phosphate dehydrogenase (G6PD) deficiency is described. The method involves the collection of blood samples on filter paper and depends on the fluorescence of reduced nicotinamide adenine dinucleotide phosphate. Simple and inexpensive to perform, this test yields positive results when enzyme levels are less than 25% of normal, thus permitting the easy detection of hemizygous men and homozygous women with G6PD deficiency. This test may give positive results in some heterozygous female carriers.
ASJC Scopus subject areas
- Pathology and Forensic Medicine