Simplified microneutralization test for serotyping adenovirus isolates

M. D. Malasig, P. R. Goswami, L. K. Crawford-Miksza, D. P. Schnurr, G. C. Gray

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

A simplified microneutralization procedure is described that uses an empirically determined virus challenge dose, a single dilution of antiserum, and observation of cytopathic effect to determine the adenovirus serotype. The simplified test has faster turnaround time and was 96% concordant with a confirmatory test using serial dilutions of type-specific sera. This method will find utility in high-volume serotyping work.

Original languageEnglish (US)
Pages (from-to)2984-2986
Number of pages3
JournalJournal of Clinical Microbiology
Volume39
Issue number8
DOIs
StatePublished - 2001
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)

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