Simulating the dynamics of an aortic valve prosthesis in a pulse duplicator: Numerical methods and initial experience

Boyce E. Griffith; Vittoria Flamini; Abe DeAnda; Lawrence Scotten

doi:10.1115/1.4025768

Simulating the dynamics of an aortic valve prosthesis in a pulse duplicator: Numerical methods and initial experience

Boyce E. Griffith, Vittoria Flamini, Abe DeAnda, Lawrence Scotten

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Scopus citations

Abstract

Each year, approximately 50,000 aortic valve replacement operations are performed in the United States, but despite decades of development, many of the limitations of aortic valve prostheses remain consequences of the fluid dynamics induced by the replacement valve. We aim to develop detailed fluidstructure interaction (FSI) models of aortic valve prostheses mounted within a ViVitro Systems, Inc. pulse duplicator. Here, we describe numerical methods for simulating FSI with rigid structures, such as the leaflets of a mechanical heart valve, and we present initial three-dimensional simulation studies of the fluid dynamics of a St. Jude Regent bileaflet valve prosthesis.

Original language	English (US)
Title of host publication	ASME 2013 Conference on Frontiers in Medical Devices
Subtitle of host publication	Applications of Computer Modeling and Simulation, FMD 2013
Publisher	American Society of Mechanical Engineers (ASME)
ISBN (Print)	9780791856000
DOIs	https://doi.org/10.1115/1.4025768
State	Published - 2013
Externally published	Yes
Event	ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, FMD 2013 - Washington, DC, United States Duration: Sep 11 2013 → Sep 13 2013

Publication series

Name	ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, FMD 2013

Other

Other	ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, FMD 2013
Country/Territory	United States
City	Washington, DC
Period	9/11/13 → 9/13/13

ASJC Scopus subject areas

Modeling and Simulation

Access to Document

10.1115/1.4025768

Cite this

Griffith, B. E., Flamini, V., DeAnda, A., & Scotten, L. (2013). Simulating the dynamics of an aortic valve prosthesis in a pulse duplicator: Numerical methods and initial experience. In ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, FMD 2013 Article FMD2013-16185 (ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, FMD 2013). American Society of Mechanical Engineers (ASME). https://doi.org/10.1115/1.4025768

Simulating the dynamics of an aortic valve prosthesis in a pulse duplicator: Numerical methods and initial experience. / Griffith, Boyce E.; Flamini, Vittoria; DeAnda, Abe et al.
ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, FMD 2013. American Society of Mechanical Engineers (ASME), 2013. FMD2013-16185 (ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, FMD 2013).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Griffith, BE, Flamini, V, DeAnda, A & Scotten, L 2013, Simulating the dynamics of an aortic valve prosthesis in a pulse duplicator: Numerical methods and initial experience. in ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, FMD 2013., FMD2013-16185, ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, FMD 2013, American Society of Mechanical Engineers (ASME), ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, FMD 2013, Washington, DC, United States, 9/11/13. https://doi.org/10.1115/1.4025768

Griffith BE, Flamini V, DeAnda A, Scotten L. Simulating the dynamics of an aortic valve prosthesis in a pulse duplicator: Numerical methods and initial experience. In ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, FMD 2013. American Society of Mechanical Engineers (ASME). 2013. FMD2013-16185. (ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, FMD 2013). doi: 10.1115/1.4025768

Griffith, Boyce E. ; Flamini, Vittoria ; DeAnda, Abe et al. / Simulating the dynamics of an aortic valve prosthesis in a pulse duplicator : Numerical methods and initial experience. ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, FMD 2013. American Society of Mechanical Engineers (ASME), 2013. (ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, FMD 2013).

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abstract = "Each year, approximately 50,000 aortic valve replacement operations are performed in the United States, but despite decades of development, many of the limitations of aortic valve prostheses remain consequences of the fluid dynamics induced by the replacement valve. We aim to develop detailed fluidstructure interaction (FSI) models of aortic valve prostheses mounted within a ViVitro Systems, Inc. pulse duplicator. Here, we describe numerical methods for simulating FSI with rigid structures, such as the leaflets of a mechanical heart valve, and we present initial three-dimensional simulation studies of the fluid dynamics of a St. Jude Regent bileaflet valve prosthesis.",

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AB - Each year, approximately 50,000 aortic valve replacement operations are performed in the United States, but despite decades of development, many of the limitations of aortic valve prostheses remain consequences of the fluid dynamics induced by the replacement valve. We aim to develop detailed fluidstructure interaction (FSI) models of aortic valve prostheses mounted within a ViVitro Systems, Inc. pulse duplicator. Here, we describe numerical methods for simulating FSI with rigid structures, such as the leaflets of a mechanical heart valve, and we present initial three-dimensional simulation studies of the fluid dynamics of a St. Jude Regent bileaflet valve prosthesis.

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Simulating the dynamics of an aortic valve prosthesis in a pulse duplicator: Numerical methods and initial experience

Abstract

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ASJC Scopus subject areas

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