Simultaneous congenital infection with Epstein-Barr virus and cytomegalovirus

J. H. Joncas, C. Alfieri, M. Leyritz-Wills, P. Brochu, G. Jasmin, Istvan Boldogh, E. S. Huang

Research output: Contribution to journalArticle

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Abstract

We have previously reported the persistence of the cytomegalovirus (CMV) genome in lymphoid cells in long-term cultures from an infant with congenital CMV infection. The Epstein-Barr virus (EBV) genome was also present in these cells, but the presence of congenital EBV infection was merely presumed on the basis of serologic evidence, since blood for the spontaneous establishment of a lymphoblastoid cell line in this instance was not available from the infant until three months after birth. We have now studied another infant, born to a primigravida mother, who had clinical laboratory, and pathological evidence of congenital CMV infection at birth and at autopsy (72 hours after birth). Congenital EBV infection was also confirmed in this infant.

Original languageEnglish (US)
Pages (from-to)1399-1403
Number of pages5
JournalNew England Journal of Medicine
Volume304
Issue number23
StatePublished - 1981
Externally publishedYes

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Epstein-Barr Virus Infections
Cytomegalovirus
Cytomegalovirus Infections
Parturition
Genome
Human Herpesvirus 4
Autopsy
Mothers
Lymphocytes
Cell Line

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Joncas, J. H., Alfieri, C., Leyritz-Wills, M., Brochu, P., Jasmin, G., Boldogh, I., & Huang, E. S. (1981). Simultaneous congenital infection with Epstein-Barr virus and cytomegalovirus. New England Journal of Medicine, 304(23), 1399-1403.

Simultaneous congenital infection with Epstein-Barr virus and cytomegalovirus. / Joncas, J. H.; Alfieri, C.; Leyritz-Wills, M.; Brochu, P.; Jasmin, G.; Boldogh, Istvan; Huang, E. S.

In: New England Journal of Medicine, Vol. 304, No. 23, 1981, p. 1399-1403.

Research output: Contribution to journalArticle

Joncas, JH, Alfieri, C, Leyritz-Wills, M, Brochu, P, Jasmin, G, Boldogh, I & Huang, ES 1981, 'Simultaneous congenital infection with Epstein-Barr virus and cytomegalovirus', New England Journal of Medicine, vol. 304, no. 23, pp. 1399-1403.
Joncas JH, Alfieri C, Leyritz-Wills M, Brochu P, Jasmin G, Boldogh I et al. Simultaneous congenital infection with Epstein-Barr virus and cytomegalovirus. New England Journal of Medicine. 1981;304(23):1399-1403.
Joncas, J. H. ; Alfieri, C. ; Leyritz-Wills, M. ; Brochu, P. ; Jasmin, G. ; Boldogh, Istvan ; Huang, E. S. / Simultaneous congenital infection with Epstein-Barr virus and cytomegalovirus. In: New England Journal of Medicine. 1981 ; Vol. 304, No. 23. pp. 1399-1403.
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