Sin Nombre virus (SNV) Ig isotype antibody response during acute and convalescent phases of hantavirus pulmonary syndrome

Pavel Bostik, Jorn Winter, Thomas G. Ksiazek, Pierre E. Rollin, Francois Villinger, Sherif R. Zaki, C. J. Peters, Aftab A. Ansari

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

Serum samples from 22 hantavirus pulmonary syndrome (HPS) patients were tested for Sin Nombre virus (SNV)-reactive antibodies. In the acute phase of HPS, 100% and 67% of the samples tested positive for SNV-specific immunoglobulin (Ig) M and IgA, respectively. Among the virus-specific IgG antibodies, the most prevalent were IgG3 (in 97% of samples), followed by IgG1 (70%), IgG2 (30%), and IgG4 (3%).

Original languageEnglish (US)
Pages (from-to)184-188
Number of pages5
JournalEmerging infectious diseases
Volume6
Issue number2
DOIs
StatePublished - Jan 1 2000
Externally publishedYes

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ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

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