Sin Nombre virus (SNV) Ig isotype antibody response during acute and convalescent phases of hantavirus pulmonary syndrome

Pavel Bostik, Jorn Winter, Thomas Ksiazek, Pierre E. Rollin, Francois Villinger, Sherif R. Zaki, C. J. Peters, Aftab A. Ansari

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Serum samples from 22 hantavirus pulmonary syndrome (HPS) patients were tested for Sin Nombre virus (SNV)-reactive antibodies. In the acute phase of HPS, 100% and 67% of the samples tested positive for SNV-specific immunoglobulin (Ig) M and IgA, respectively. Among the virus-specific IgG antibodies, the most prevalent were IgG3 (in 97% of samples), followed by IgG1 (70%), IgG2 (30%), and IgG4 (3%).

Original languageEnglish (US)
Pages (from-to)184-188
Number of pages5
JournalEmerging Infectious Diseases
Volume6
Issue number2
StatePublished - Mar 2000
Externally publishedYes

Fingerprint

Sin Nombre virus
Hantavirus Pulmonary Syndrome
Immunoglobulin Isotypes
Antibody Formation
Immunoglobulin G
Antibodies
Immunoglobulin A
Immunoglobulin M
Viruses
Serum

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Bostik, P., Winter, J., Ksiazek, T., Rollin, P. E., Villinger, F., Zaki, S. R., ... Ansari, A. A. (2000). Sin Nombre virus (SNV) Ig isotype antibody response during acute and convalescent phases of hantavirus pulmonary syndrome. Emerging Infectious Diseases, 6(2), 184-188.

Sin Nombre virus (SNV) Ig isotype antibody response during acute and convalescent phases of hantavirus pulmonary syndrome. / Bostik, Pavel; Winter, Jorn; Ksiazek, Thomas; Rollin, Pierre E.; Villinger, Francois; Zaki, Sherif R.; Peters, C. J.; Ansari, Aftab A.

In: Emerging Infectious Diseases, Vol. 6, No. 2, 03.2000, p. 184-188.

Research output: Contribution to journalArticle

Bostik, P, Winter, J, Ksiazek, T, Rollin, PE, Villinger, F, Zaki, SR, Peters, CJ & Ansari, AA 2000, 'Sin Nombre virus (SNV) Ig isotype antibody response during acute and convalescent phases of hantavirus pulmonary syndrome', Emerging Infectious Diseases, vol. 6, no. 2, pp. 184-188.
Bostik, Pavel ; Winter, Jorn ; Ksiazek, Thomas ; Rollin, Pierre E. ; Villinger, Francois ; Zaki, Sherif R. ; Peters, C. J. ; Ansari, Aftab A. / Sin Nombre virus (SNV) Ig isotype antibody response during acute and convalescent phases of hantavirus pulmonary syndrome. In: Emerging Infectious Diseases. 2000 ; Vol. 6, No. 2. pp. 184-188.
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