Sin Nombre virus (SNV) Ig isotype antibody response during acute and convalescent phases of hantavirus pulmonary syndrome

Pavel Bostik; Jorn Winter; Thomas G. Ksiazek; Pierre E. Rollin; Francois Villinger; Sherif R. Zaki; C. J. Peters; Aftab A. Ansari

doi:10.3201/eid0602.000213

Sin Nombre virus (SNV) Ig isotype antibody response during acute and convalescent phases of hantavirus pulmonary syndrome

Pavel Bostik, Jorn Winter, Thomas G. Ksiazek, Pierre E. Rollin, Francois Villinger, Sherif R. Zaki, C. J. Peters, Aftab A. Ansari

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

Serum samples from 22 hantavirus pulmonary syndrome (HPS) patients were tested for Sin Nombre virus (SNV)-reactive antibodies. In the acute phase of HPS, 100% and 67% of the samples tested positive for SNV-specific immunoglobulin (Ig) M and IgA, respectively. Among the virus-specific IgG antibodies, the most prevalent were IgG3 (in 97% of samples), followed by IgG1 (70%), IgG2 (30%), and IgG4 (3%).

Original language	English (US)
Pages (from-to)	184-188
Number of pages	5
Journal	Emerging infectious diseases
Volume	6
Issue number	2
DOIs	https://doi.org/10.3201/eid0602.000213
State	Published - 2000
Externally published	Yes

ASJC Scopus subject areas

Epidemiology
Microbiology (medical)
Infectious Diseases

Access to Document

10.3201/eid0602.000213

Cite this

@article{ef7d5d30b0cc44dd9f160e03403d8108,

title = "Sin Nombre virus (SNV) Ig isotype antibody response during acute and convalescent phases of hantavirus pulmonary syndrome",

abstract = "Serum samples from 22 hantavirus pulmonary syndrome (HPS) patients were tested for Sin Nombre virus (SNV)-reactive antibodies. In the acute phase of HPS, 100\% and 67\% of the samples tested positive for SNV-specific immunoglobulin (Ig) M and IgA, respectively. Among the virus-specific IgG antibodies, the most prevalent were IgG3 (in 97\% of samples), followed by IgG1 (70\%), IgG2 (30\%), and IgG4 (3\%).",

author = "Pavel Bostik and Jorn Winter and Ksiazek, \{Thomas G.\} and Rollin, \{Pierre E.\} and Francois Villinger and Zaki, \{Sherif R.\} and Peters, \{C. J.\} and Ansari, \{Aftab A.\}",

year = "2000",

doi = "10.3201/eid0602.000213",

language = "English (US)",

volume = "6",

pages = "184--188",

journal = "Emerging infectious diseases",

issn = "1080-6040",

publisher = "Centers for Disease Control and Prevention (CDC)",

number = "2",

}

TY - JOUR

T1 - Sin Nombre virus (SNV) Ig isotype antibody response during acute and convalescent phases of hantavirus pulmonary syndrome

AU - Bostik, Pavel

AU - Winter, Jorn

AU - Ksiazek, Thomas G.

AU - Rollin, Pierre E.

AU - Villinger, Francois

AU - Zaki, Sherif R.

AU - Peters, C. J.

AU - Ansari, Aftab A.

PY - 2000

Y1 - 2000

N2 - Serum samples from 22 hantavirus pulmonary syndrome (HPS) patients were tested for Sin Nombre virus (SNV)-reactive antibodies. In the acute phase of HPS, 100% and 67% of the samples tested positive for SNV-specific immunoglobulin (Ig) M and IgA, respectively. Among the virus-specific IgG antibodies, the most prevalent were IgG3 (in 97% of samples), followed by IgG1 (70%), IgG2 (30%), and IgG4 (3%).

AB - Serum samples from 22 hantavirus pulmonary syndrome (HPS) patients were tested for Sin Nombre virus (SNV)-reactive antibodies. In the acute phase of HPS, 100% and 67% of the samples tested positive for SNV-specific immunoglobulin (Ig) M and IgA, respectively. Among the virus-specific IgG antibodies, the most prevalent were IgG3 (in 97% of samples), followed by IgG1 (70%), IgG2 (30%), and IgG4 (3%).

UR - https://www.scopus.com/pages/publications/0034050101

UR - https://www.scopus.com/inward/citedby.url?scp=0034050101&partnerID=8YFLogxK

U2 - 10.3201/eid0602.000213

DO - 10.3201/eid0602.000213

M3 - Article

C2 - 10756154

AN - SCOPUS:0034050101

SN - 1080-6040

VL - 6

SP - 184

EP - 188

JO - Emerging infectious diseases

JF - Emerging infectious diseases

IS - 2

ER -

Sin Nombre virus (SNV) Ig isotype antibody response during acute and convalescent phases of hantavirus pulmonary syndrome

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this