Sin Nombre virus (SNV) Ig isotype antibody response during acute and convalescent phases of hantavirus pulmonary syndrome

Pavel Bostik; Jorn Winter; Thomas G. Ksiazek; Pierre E. Rollin; Francois Villinger; Sherif R. Zaki; C. J. Peters; Aftab A. Ansari

doi:10.3201/eid0602.000213

Sin Nombre virus (SNV) Ig isotype antibody response during acute and convalescent phases of hantavirus pulmonary syndrome

Pavel Bostik
, Jorn Winter
, Thomas G. Ksiazek
, Pierre E. Rollin
, Francois Villinger
, Sherif R. Zaki
, C. J. Peters
, Aftab A. Ansari

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

Serum samples from 22 hantavirus pulmonary syndrome (HPS) patients were tested for Sin Nombre virus (SNV)-reactive antibodies. In the acute phase of HPS, 100% and 67% of the samples tested positive for SNV-specific immunoglobulin (Ig) M and IgA, respectively. Among the virus-specific IgG antibodies, the most prevalent were IgG3 (in 97% of samples), followed by IgG1 (70%), IgG2 (30%), and IgG4 (3%).

Original language	English (US)
Pages (from-to)	184-188
Number of pages	5
Journal	Emerging infectious diseases
Volume	6
Issue number	2
DOIs	https://doi.org/10.3201/eid0602.000213
State	Published - 2000
Externally published	Yes

ASJC Scopus subject areas

Epidemiology
Microbiology (medical)
Infectious Diseases

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10.3201/eid0602.000213

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title = "Sin Nombre virus (SNV) Ig isotype antibody response during acute and convalescent phases of hantavirus pulmonary syndrome",

abstract = "Serum samples from 22 hantavirus pulmonary syndrome (HPS) patients were tested for Sin Nombre virus (SNV)-reactive antibodies. In the acute phase of HPS, 100\% and 67\% of the samples tested positive for SNV-specific immunoglobulin (Ig) M and IgA, respectively. Among the virus-specific IgG antibodies, the most prevalent were IgG3 (in 97\% of samples), followed by IgG1 (70\%), IgG2 (30\%), and IgG4 (3\%).",

author = "Pavel Bostik and Jorn Winter and Ksiazek, \{Thomas G.\} and Rollin, \{Pierre E.\} and Francois Villinger and Zaki, \{Sherif R.\} and Peters, \{C. J.\} and Ansari, \{Aftab A.\}",

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doi = "10.3201/eid0602.000213",

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T1 - Sin Nombre virus (SNV) Ig isotype antibody response during acute and convalescent phases of hantavirus pulmonary syndrome

AU - Bostik, Pavel

AU - Winter, Jorn

AU - Ksiazek, Thomas G.

AU - Rollin, Pierre E.

AU - Villinger, Francois

AU - Zaki, Sherif R.

AU - Peters, C. J.

AU - Ansari, Aftab A.

PY - 2000

Y1 - 2000

N2 - Serum samples from 22 hantavirus pulmonary syndrome (HPS) patients were tested for Sin Nombre virus (SNV)-reactive antibodies. In the acute phase of HPS, 100% and 67% of the samples tested positive for SNV-specific immunoglobulin (Ig) M and IgA, respectively. Among the virus-specific IgG antibodies, the most prevalent were IgG3 (in 97% of samples), followed by IgG1 (70%), IgG2 (30%), and IgG4 (3%).

AB - Serum samples from 22 hantavirus pulmonary syndrome (HPS) patients were tested for Sin Nombre virus (SNV)-reactive antibodies. In the acute phase of HPS, 100% and 67% of the samples tested positive for SNV-specific immunoglobulin (Ig) M and IgA, respectively. Among the virus-specific IgG antibodies, the most prevalent were IgG3 (in 97% of samples), followed by IgG1 (70%), IgG2 (30%), and IgG4 (3%).

UR - https://www.scopus.com/pages/publications/0034050101

UR - https://www.scopus.com/pages/publications/0034050101#tab=citedBy

U2 - 10.3201/eid0602.000213

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JO - Emerging infectious diseases

JF - Emerging infectious diseases

IS - 2

ER -

Sin Nombre virus (SNV) Ig isotype antibody response during acute and convalescent phases of hantavirus pulmonary syndrome

Abstract

ASJC Scopus subject areas

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